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Novel Technologies for Vaccine Development

  • Book
  • © 2014

Overview

Editors:
  1. Igor S Lukashevich

    1. Department of Pharmacology and Toxicolog Department of Microbiology and Immunolog, University of Louisville, Louisville, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Haval Shirwan

    1. Department of Microbiology and Immunolog, University of Louisville, Louisville, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Written by selected experts from academia and industry

  • Gives a broad and translational overview to the topic

  • Comprehensive volume on viral vector vaccines ?with focus on different cases of vaccine development

  • Includes supplementary material: sn.pub/extras

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About this book

This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Preventive Viral-Vectored Vaccines

    1. Front Matter

      Pages 1-1
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    2. Reverse Genetics Approaches for Rational Design of Inactivated and Live Attenuated Influenza Vaccines

      • Yoshihiro Kawaoka, Gabriele Neumann
      Pages 3-32

    3. Viral-Vectored Vaccines to Control Pathogenic Filoviruses

      • Chad E. Mire, Thomas W. Geisbert
      Pages 33-60

    4. Alphavirus Replicon Vectors for Prophylactic Applications and Cancer Intervention

      • Peter Pushko, Irina Tretyakova
      Pages 61-85

    5. Current Status and Future of Polio Vaccines and Vaccination

      • Konstantin Chumakov
      Pages 87-112

    6. Current Status of Hantavirus Vaccines Development

      • Evgeniy A. Tkachenko, Tamara K. Dzagurova, Peter E. Tkachenko
      Pages 113-151

    7. Experimental DNA-Launched Live-Attenuated Vaccines Against Infections Caused by Flavi- and Alphaviruses

      • Peter Pushko, Peter P. Bredenbeek, Igor S. Lukashevich
      Pages 153-177

    8. Sugar-Based Immune Adjuvants for Use in Recombinant, Viral Vector, DNA and Other Styles of Vaccines

      • Nikolai Petrovsky
      Pages 179-200

  3. Viral-Vectored Therapeutic Cancer Vaccines

    1. Front Matter

      Pages 201-201
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    2. Adenovirus-Based Vectors for the Development of Prophylactic and Therapeutic Vaccines

      • Anton V. Borovjagin, Jorge G. Gomez-Gutierrez, Haval Shirwan, Qiana L. Matthews
      Pages 203-271

    3. Radiovirotherapy for the Treatment of Cancer

      • Kevin J. Harrington
      Pages 273-290

    4. TRICOM Poxviral-Based Vaccines for the Treatment of Cancer

      • Caroline Jochems, Jeffrey Schlom, James L. Gulley
      Pages 291-327

    5. The Use of Oncolytic Herpesvirus for the Treatment of Cancer

      • Tasha Hughes, Howard L. Kaufman
      Pages 329-345

    6. SA-4-1BBL: A Novel Form of the 4-1BB Costimulatory Ligand as an Adjuvant Platform for the Development of Subunit Cancer Vaccines

      • Rajesh K. Sharma, Abhishek K. Srivastava, Hong Zhao, Esma S. Yolcu, Haval Shirwan
      Pages 347-386
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Editors and Affiliations

  • Department of Pharmacology and Toxicolog Department of Microbiology and Immunolog, University of Louisville, Louisville, USA

    Igor S Lukashevich

  • Department of Microbiology and Immunolog, University of Louisville, Louisville, USA

    Haval Shirwan

Bibliographic Information

  • Book Title: Novel Technologies for Vaccine Development

  • Editors: Igor S Lukashevich, Haval Shirwan

  • DOI: https://doi.org/10.1007/978-3-7091-1818-4

  • Publisher: Springer Vienna

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Wien 2014

  • Hardcover ISBN: 978-3-7091-1817-7Published: 01 December 2014

  • Softcover ISBN: 978-3-7091-1980-8Published: 22 September 2016

  • eBook ISBN: 978-3-7091-1818-4Published: 13 November 2014

  • Edition Number: 1

  • Number of Pages: XIV, 386

  • Number of Illustrations: 2 b/w illustrations, 33 illustrations in colour

  • Topics: Vaccine, Pharmaceutical Sciences/Technology, Immunology

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