Molecular Parasitology

Protozoan Parasites and their Molecules

  • Julia Walochnik
  • Michael Duchêne

Table of contents

  1. Front Matter
    Pages i-ix
  2. The Molecules

    1. Front Matter
      Pages 1-1
    2. Omar S. Harb, Ulrike Boehme, Kathryn Crouch, Olukemi O. Ifeonu, David S. Roos, Joana C. Silva et al.
      Pages 3-48
    3. Jonathan Wastling, Dong Xia
      Pages 49-74
    4. Iain B. H. Wilson
      Pages 75-89
  3. The Parasites (and Their Molecules)

    1. Front Matter
      Pages 91-91
    2. Norbert Müller, Joachim Müller
      Pages 93-114
    3. Pier Luigi Fiori, Paola Rappelli, Daniele Dessì, Robert Hirt, Sven Gould, Jan Tachezy et al.
      Pages 115-155
    4. Christine Clayton
      Pages 157-194
    5. Anton Aebischer, Martin Mrva
      Pages 195-216
    6. Carsten G. K. Lüder, Frank Seeber
      Pages 217-239
    7. Volker Heussler, Tobias Spielmann, Friedrich Frischknecht, Tim Gilberger
      Pages 241-284
    8. Martina Köhsler, Martin Mrva, Julia Walochnik
      Pages 285-324
    9. Michael Duchêne
      Pages 325-379
  4. Hot Topics

    1. Front Matter
      Pages 381-381
    2. Christen M. Klinger, Anna Karnkowska, Emily K. Herman, Vladimir Hampl, Joel B. Dacks
      Pages 383-408
    3. Heinrich Körner, Shanshan Hu, Christian Bogdan
      Pages 409-430
    4. Günter A. Schaub, Patric Vogel, Carsten Balczun
      Pages 431-489
    5. Pascal Mäser, Reto Brun
      Pages 491-507
    6. Julie Healer, Alan F. Cowman
      Pages 509-525

About this book

Introduction

In the past years, genome projects for numerous human parasites have been completed and now allow first in depth comparisons and evolutionary conclusions. The genomes of parasites reflect the coevolution with their host, metabolic capacities depending on their respective habitat in the host. Gut parasites usually have an anaerobic metabolism, while blood parasites have an aerobic metabolism, intracellular parasites escape the immune system, while extracellular parasites evade the immune system, usually by antigenic variation. Comprehensive genome data now being available allow us to address profound scientific questions, such as which traits enable the parasite to survive in the human host, which to cause disease and which can be used as drug targets. This book intends to give an overview of the state of knowledge on “the molecules” of protozoan parasites – on their genomes, proteomes, glycomes and lipidomes.

Keywords

Trypanosoma Tropical Medicine Leishmania Host parasite co-evolution drug design

Editors and affiliations

  • Julia Walochnik
    • 1
  • Michael Duchêne
    • 2
  1. 1.Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of ViennaViennaAustria
  2. 2.Institute of Specific Prophylaxis and Tropical Medicine, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna ViennaAustria

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-7091-1416-2
  • Copyright Information Springer-Verlag Wien 2016
  • Publisher Name Springer, Vienna
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-7091-1415-5
  • Online ISBN 978-3-7091-1416-2
  • About this book