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  • © 2011

Bacterial Lipopolysaccharides

Structure, Chemical Synthesis, Biogenesis and Interaction with Host Cells

  • Updates the current knowledge concerning the lipopolysaccharide
  • New aspects of their physicochemical biology are introduced
  • Emphasis is placed on the fine chemical structure
  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xi
  2. Lipid A Structure

    • Alba Silipo, Antonio Molinaro
    Pages 1-20
  3. Structure of O-Antigens

    • Yuriy A. Knirel
    Pages 41-115
  4. Chemical Synthesis of Lipid A and Analogues

    • Shoichi Kusumoto
    Pages 117-130
  5. Chemical Synthesis of Lipopolysaccharide Core

    • Paul Kosma, Alla Zamyatina
    Pages 131-161
  6. Genetics and Biosynthesis of Lipid A

    • Christopher M. Stead, Aaron C. Pride, M. Stephen Trent
    Pages 163-193
  7. Pathways for the Biosynthesis of NDP Sugars

    • Youai Hao, Joseph S. Lam
    Pages 195-235
  8. Lipopolysaccharide Core Oligosaccharide Biosynthesis and Assembly

    • Uwe Mamat, Mikael Skurnik, José Antonio Bengoechea
    Pages 237-273
  9. Genetics, Biosynthesis and Assembly of O-Antigen

    • Miguel A. Valvano, Sarah E. Furlong, Kinnari B. Patel
    Pages 275-310
  10. Lipopolysaccharide Export to the Outer Membrane

    • Paola Sperandeo, Gianni Dehò, Alessandra Polissi
    Pages 311-337
  11. Evolution of Lipopolysaccharide Biosynthesis Genes

    • Monica M. Cunneen, Peter R. Reeves
    Pages 339-370
  12. The Molecular Basis of Lipid A and Toll-Like Receptor 4 Interactions

    • Georgina L. Hold, Clare E. Bryant
    Pages 371-387
  13. Modulation of Lipopolysaccharide Signalling Through TLR4 Agonists and Antagonists

    • Francesco Peri, Matteo Piazza, Valentina Calabrese, Roberto Cighetti
    Pages 389-416
  14. Lipopolysaccharide and Its Interactions with Plants

    • Gitte Erbs, Mari-Anne Newman
    Pages 417-433
  15. Back Matter

    Pages 435-440

About this book

The bacterial lipopolysaccharide also known as endotoxin is exhaustively covered in the present work. Central emphasis is placed upon the fine chemical structure of the lipopolysaccharide and its significance for understanding their activity and function. In particular, the role it plays in the interaction of bacteria with other biological systems is examined. New aspects of their physicochemical biology are introduced and updates to the current knowledge concerning the lipopolysaccharide are provided. This important class of biomolecules has recently attracted the attention of many investigators, in particular for understanding its involvement in innate immunity, toll-like receptor recognition and intracellular signaling.

Editors and Affiliations

  • N.D. Zelinsky Institute of Organic Chemi, Russian Academy of Sciences, Moscow, V-334, Russian Federation

    Yuriy A. Knirel

  • Centre for Human Immunology and, Department of Microbiology and Immunolog, University of Western Ontario, London, Canada

    Miguel A. Valvano

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access