Percutaneous Penetration Enhancers Physical Methods in Penetration Enhancement

1. Front Matter

   Pages i-xvii

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2. Sonophoresis in Penetration Enhancement

   1. Front Matter

      Pages 1-1

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   2. Sonophoresis: Ultrasound-Mediated Transdermal Drug Delivery

      • Samir Mitragotri

      Pages 3-14

   3. The Mechanism of Sonophoresis and the Penetration Pathways

      • Sang Eun Lee, Jongbum Seo, Seung Hun Lee

      Pages 15-30

   4. Therapeutic Applications of Sonophoresis and Sonophoretic Devices

      • José Juan Escobar-Chávez, Roberto Díaz-Torres, Clara Luisa Domínguez-Delgado, Isabel Marlen Rodríguez-Cruz, Raquel López-Arellano, Elvia Adriana Morales Hipólito

      Pages 31-58

3. Iontophoresis in Penetration Enhancement

   1. Front Matter

      Pages 59-59

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   2. Iontophoresis: Basic Principles

      • Taís Gratieri, Yogeshvar N. Kalia

      Pages 61-65

   3. Iontophoretic Transport Mechanisms and Factors Affecting Electrically Assisted Delivery

      • Taís Gratieri, Yogeshvar N. Kalia

      Pages 67-76

   4. Iontophoresis for Therapeutic Drug Delivery and Non-invasive Sampling Applications

      • Virginia Merino, Alicia López Castellano, M. Begoña Delgado-Charro

      Pages 77-101

4. Electroporation in Penetration Enhancement

   1. Front Matter

      Pages 103-103

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   2. Electroporation for Dermal and Transdermal Drug Delivery

      • Babu M. Medi, Buddhadev Layek, Jagdish Singh

      Pages 105-122

   3. Therapeutic Applications of Electroporation

      • Muralikrishnan Angamuthu, S. Narasimha Murthy

      Pages 123-137

5. Novel Electrochemical Devices

   1. Front Matter

      Pages 139-139

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   2. An Electrochemical Transdermal Patch for Permeation Enhancement

      • Geoffrey Lee, Britta Schröder, Ulrich Nickel, Elisabeth Meyer

      Pages 141-157

6. Different Waves in Penetration Enhancement

   1. Front Matter

      Pages 159-159

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   2. Microwaves as a Skin Permeation Enhancement Method

      • Hamid R. Moghimi, Azadeh Alinaghi

      Pages 161-174

   3. Photoacoustic Waves as a Skin Permeation Enhancement Method

      • Gonçalo F. F. Sá, Carlos Serpa, Luis G. Arnaut

      Pages 175-191

7. The Use of Magnetic Fields in Penetration Enhancement

   1. Front Matter

      Pages 193-193

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   2. Magnetophoresis: Skin Penetration Enhancement by a Magnetic Field

      • Heather A. E. Benson, Matthew McIldowie, Tarl Prow

      Pages 195-206

8. Moxibustion in Penetration Enhancement

   1. Front Matter

      Pages 207-207

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Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered, and the latest findings are provided on skin structure and function, mathematics in skin permeation, and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners, and also students.​

• Electroporation
• Neddle-free jet injections
• Sonophoresis and iontophoresis
• Transdermal delivery of peptides and proteins
• Vesicles under voltage

• Apoteka “Beograd”, Belgrade, Serbia

  Nina Dragicevic

• San Francisco, USA

  Howard I. Maibach

Howard I. Maibach is Professor of Dermatology at the University of California, San Francisco. He is a leading authority in the fields of dermatotoxicology and dermatopharmacology, in which he has conducted much original research and written very extensively, with a total of more than 2,500 publications as lead or co-author. Professor Maibach has served on the editorial boards of more than 30 scientific journals and is a member of many professional societies, including the American Academy of Dermatology and the International Commission on Occupational Health. He has also been the recipient of numerous honors, both within the United States and overseas. Nina Dragićević-Ćurić graduated from the University of Belgrade, Faculty of Pharmacy in 1999 and subsequently obtained an MSc and a PhD (summa cum laude, Dr. rer. nat.) in Pharmaceutical Technology from the University of Belgrade and the Friedrich-Schiller University, Jena, respectively. Dr. Dragićević-Ćurić is an accredited Specialist in Pharmaceutical Technology. Since 2007 she has been responsible for the preparation of compounded drugs in pharmacies of the state pharmaceutical company “Apoteka Beograd” in Belgrade. She has published in a variety of international journals.

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