Transgenic Animals as Model Systems for Human Diseases

  • Erwin F. Wagner
  • Franz Theuring
Conference proceedings

Part of the Schering Foundation Workshop book series (SCHERING FOUND, volume 6)

Table of contents

  1. Front Matter
    Pages I-XII
  2. Edward Rubin, Joshua Schultz
    Pages 25-37
  3. Charles Weissmann, Hansruedi Büeler, Marek Fischer, Michel Aguet
    Pages 39-56
  4. Rachael L. Neve, Michael R. Kozlowski, Anja Kammerscheidt, Christine F. Hohmann
    Pages 57-72
  5. Lothar Hennighausen, Avi Shamay, Priscilla A. Furth, Robert A. McKnight, Caird Rexroad Jr., Vern G. Pursel et al.
    Pages 129-141
  6. Michael A. Rudnicki, Thomas Braun, Hans-Henning Arnold, Rudolf Jaenisch
    Pages 143-151

About these proceedings


Some of the current concepts used in transgenic research, an increasingly important tool to study the regulation and function of genes, are illustrated in this book. With these techniques, animal models can be used to study human diseases; this opens up new possibilities in both applied and basic research. Specifically, the ability to introduce genes into the germline of mice and the successful expression of the inserted gene within an organism provide new insights and opportunities for biomedical research. The discussion here shows how a detailed analysis of the underlying molecular mechanisms will provide new insights into the genetic origin of certain diseases and will lead to a better understanding of normal and abnormal physiological processes.


Biomedizinische Forschung Gentechnologie Labormedizin biomedical engineering gene genetic engineering genetics medicine microbiology virus

Editors and affiliations

  • Erwin F. Wagner
    • 1
  • Franz Theuring
  1. 1.Research Institute of Molecular Pathology (IMP)ViennaAustria

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-02927-5
  • Online ISBN 978-3-662-02925-1
  • Series Print ISSN 0947-6075
  • Buy this book on publisher's site