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Human Genetics

Problems and Approaches

  • Friedrich Vogel
  • Arno G. Motulsky

Table of contents

  1. Front Matter
    Pages I-XXXIV
  2. Friedrich Vogel, Arno G. Motulsky
    Pages 1-8
  3. Friedrich Vogel, Arno G. Motulsky
    Pages 9-19
  4. Friedrich Vogel, Arno G. Motulsky
    Pages 20-110
  5. Friedrich Vogel, Arno G. Motulsky
    Pages 111-227
  6. Friedrich Vogel, Arno G. Motulsky
    Pages 228-333
  7. Friedrich Vogel, Arno G. Motulsky
    Pages 334-432
  8. Friedrich Vogel, Arno G. Motulsky
    Pages 433-511
  9. Friedrich Vogel, Arno G. Motulsky
    Pages 512-542
  10. Friedrich Vogel, Arno G. Motulsky
    Pages 543-613
  11. Back Matter
    Pages 642-810

About this book

Introduction

The first edition of this book, published in 1979, was found useful by many stu­ dents and was well received by the scientific community. Since the book was first written, human genetics has undergone dramatic developments, mainly due to the introduction of new concepts and techniques from molecular biology. Con­ comitantly, "basic" scientists have become increasingly interested in problems of human genetics. More than 700 human genes have been mapped, genes of previ­ ously unsuspected complexity -such as the gene for factor VIII - have become known, and the structure of noncoding DNA sequences is being analyzed with the aim of understanding gene regulation. DNA diagnosis is being rapidly intro­ duced into medical genetics. All this, as well as the extensive progress in most other fields of human and medical genetics, had to be considered in the prepara­ tion of this second edition. The book has been extensively revised and rewritten. A substantial new section dealing with gene and chromosomal structure at the molecular level has been added. The newer knowledge of molecular genetics has been incorporated, and the conceptual and practical contribution of DNA methods (for example in the hemoglobinopathies and in some other diseases) is discussed. Many new figures and tables have been added, and some illustrative material has been replaced. We have read carefully the many friendly and sometimes flattering reviews of the first edition.

Keywords

Chromosom DNA Genetic Analysis gene therapy genes genetics heredity human development human evolution inborn diseases prenatal diagnosis

Authors and affiliations

  • Friedrich Vogel
    • 1
  • Arno G. Motulsky
    • 2
  1. 1.Institut für Anthropologie und HumangenetikHeidelbergGermany
  2. 2.Division of Medical GeneticsUniversity of WashingtonSeattleUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-662-02489-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-662-02491-1
  • Online ISBN 978-3-662-02489-8
  • Buy this book on publisher's site