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Testosterone

Action - Deficiency - Substitution

  • Book
  • © 1990

Overview

Editors:
  1. Eberhard Nieschlag

    1. Institute of Reproductive Medicine, University of Münster, Münster, Federal Republic of Germany

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  2. Hermann M. Behre

    1. Institute of Reproductive Medicine, University of Münster, Münster, Federal Republic of Germany

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XI
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  2. Testosterone: an overview of biosynthesis, transport, metabolism and action

    • Focko F. G. Rommerts
    Pages 1-22

  3. The role of testosterone in spermatogenesis

    • Gerhard F. Weinbauer, Eberhard Nieschlag
    Pages 23-50

  4. Psychotropic effects of testosterone

    • Walter Hubert
    Pages 51-71

  5. Syndromes caused by androgen resistance

    • Hans-Udo Schweikert, Gabriela Romalo
    Pages 72-91

  6. Pharmacology and clinical uses of testosterone

    • Eberhard Nieschlag, Hermann M. Behre
    Pages 92-114

  7. Comparative pharmacokinetics of androgen preparations: Application of computer analysis and simulation

    • Hermann M. Behre, Frank Oberpenning, Eberhard Nieschlag
    Pages 115-135

  8. Pharmacology of testosterone pellet implants

    • David J. Handelsman
    Pages 136-154

  9. Percutaneous dihydrotestosterone (DHT) treatment

    • Gilbert Schaison, Khalil Nahoul, Béatrice Couzinet
    Pages 155-164

  10. Transdermal testosterone replacement through genital skin

    • Virgil A. Place, Linda Atkinson, Della A. Prather, Nancy Trunnell, F. Eugene Yates
    Pages 165-181

  11. Safety aspects of androgen therapy

    • Louis J. G. Gooren, Kaas H. Polderman
    Pages 182-203

  12. Effects of androgens on bone metabolism

    • Joel S. Finkelstein, Anne Klibanski
    Pages 204-218

  13. Androgens and human benign prostatic hyperplasia (BPH)

    • Michael Krieg, Sabine Tunn
    Pages 219-244

  14. Androgens and carcinoma of the prostate

    • Fritz H. Schröder
    Pages 245-260

  15. Androgens and male senescence

    • Alex Vermeulen
    Pages 261-276

  16. Back Matter

    Pages 277-285
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Keywords

About this book

New developments in testosterone therapy are summarized here by internationally renowned experts. They review both basic and clinical knowledge in fourteen chapters. The book begins with the biochemistry of testosterone, its biosynthesis, metabolism and mechanisms of action in target organs. Three chapters deal with specific aspects of testosterone action, namely its role in spermatogenesis, its psychotropic effects and its effects on bones. Syndromes caused by androgen resistance are described in order to highlight the importance of properly functioning enzymes and receptors in the target organs. Causes and symptoms of male hypogonadism, the major indication for testosterone treatment, are described. Five chapters are devoted to the pharmacology, pharmacokinetics and clinical uses and abuses of testosterone preparations. The new transdermal testosterone application is described in detail. Side effects of testosterone treatment are reviewed. The possible role of androgens in the development of prostatic hypertrophy and carcinoma is discussed extensively since this question is of major concern to the clinician.

Editors and Affiliations

  • Institute of Reproductive Medicine, University of Münster, Münster, Federal Republic of Germany

    Eberhard Nieschlag, Hermann M. Behre

Bibliographic Information

  • Book Title: Testosterone

  • Book Subtitle: Action - Deficiency - Substitution

  • Editors: Eberhard Nieschlag, Hermann M. Behre

  • DOI: https://doi.org/10.1007/978-3-662-00814-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1990

  • eBook ISBN: 978-3-662-00814-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 285

  • Number of Illustrations: 78 b/w illustrations

  • Topics: Pharmacology/Toxicology, Dermatology, Gynecology

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