The Geometry of Population Genetics

  • Ethan Akin

Part of the Lecture Notes in Biomathematics book series (LNBM, volume 31)

Table of contents

  1. Front Matter
    Pages I-IV
  2. Ethan Akin
    Pages 1-2
  3. Ethan Akin
    Pages 80-118
  4. Ethan Akin
    Pages 119-172
  5. Ethan Akin
    Pages 173-190
  6. Back Matter
    Pages 191-208

About this book

Introduction

The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono­ graph I hope to show that his ideas illuminate many aspects of pop­ ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele model of selection plus recombination even when the fitness numbers are constant (i.e. no frequency dependence). This work is addressed to two different kinds of readers which accounts for its mode of organization. For the biologist, Chapter I contains a description of the entire work with brief indications of a proof for the harder results. I imagine a reader with some familiarity with linear algebra and systems of differential equations. Ideal background is Hirsch and Smale's text [15].

Keywords

Differentialtopologie Manifold Population Populationsgenetik calculus differential equarions differential geometry equation geometry theorem

Authors and affiliations

  • Ethan Akin
    • 1
  1. 1.Mathematics DepartmentThe City CollegeNew York CityUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-93128-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1979
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-09711-2
  • Online ISBN 978-3-642-93128-4
  • Series Print ISSN 0341-633X
  • About this book