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Mild hypertension

Current controversies and new approaches

  • Book
  • © 1984

Overview

Editors:
  1. M. A. Weber

    1. Hypertension Center, Veterans Administration Center, Long Beach, USA

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  2. C. J. Mathias

    1. Medical Unit, St. Mary’s Hospital Medical School, London, Great Britain

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    You can also search for this editor in PubMed   Google Scholar

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Table of contents (21 chapters)

  1. Front Matter

    Pages I-VIII
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  2. Introduction: Some neurological aspects of blood pressure control

    1. Introduction: Some neurological aspects of blood pressure control

      • W. S. Peart
      Pages 1-7

  3. Central and peripheral control of blood pressure

    1. Front Matter

      Pages 9-9
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    2. Central nervous system control of blood pressure

      • Ronald J. Polinsky
      Pages 11-23

    3. Blood pressure control and the peripheral sympathetic nervous system

      • C. J. Mathias
      Pages 24-33

    4. Baroreflex function and centrally acting antihypertensive drugs

      • Gordon P. Guthrie Jr.
      Pages 34-42

    5. Haemodynamic effects of antihypertensive agents in man

      • G. Mancia, A. Zanchetti
      Pages 43-50

    6. Vascular autonomy and its relation to the action of antihypertensive drugs

      • J. G. Collier
      Pages 51-61

  4. Therapeutic consequences

    1. Front Matter

      Pages 63-63
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    2. Therapeutic decisions in mild hypertension: an introductory overview

      • Stanley S. Franklin
      Pages 65-71

    3. When to treat? Recent trials in mild hypertension. Epidemiological data and conclusions

      • K. Hayduk
      Pages 72-77

    4. Current assessment of the stepped-care treatment of mild hypertension: diuretics, beta-blockers, vasodilators versus Clonidine

      • M. P. Sambhi
      Pages 78-87

    5. Use of centrally-acting agonists in the treatment of mild hypertension in the elderly patient

      • J. I. M. Drayer, M. A. Weber
      Pages 88-95

    6. Sympathetic nervous system activity in the obese hypertensive patient: potential role for central alpha-adrenoreceptor agonists

      • Michael Tuck
      Pages 96-108

    7. Clonidine for treating patients with mild hypertension and angina pectoris

      • T. Zaleska, L. Ceremużyński
      Pages 109-117

    8. New pharmacological approaches in the treatment of mild hypertension. The potential role of converting enzyme inhibitors and calcium blocking agents

      • F. Alhenc-Gelas, P. Corvol, J. Menard
      Pages 118-126

  5. Advances in treatment

    1. Front Matter

      Pages 129-129
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    2. Rate-controlled drug delivery and the reduction of risk

      • K. Heilmann
      Pages 131-133

    3. Clonidine rate — controlled system: technology and kinetics

      • J. E. Shaw, D. Enscore, L. Chu
      Pages 134-142

    4. Absorption of clonidine from a transdermal therapeutic system when applied to different body sites

      • K. Hopkins, L. Aarons, M. Rowland
      Pages 143-147
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Keywords

About this book

There is clear evidence that in severe hypertension lowering blood pressure, by drug therapy decreases the incidence of major cardiovascular events. Recent studies suggest that such benefit may also extend to patients with mild to moderate hypertension. The putative benefits of drugs may be offset, however, by their adverse effects and a prime example is the increased incidence of impotence and metabolic disorders in patients on thiazide diuretics. There is, therefore, a real need to look further into the therapy of patients with mild to moderate hypertension. The ideal drug in such patients would oppose the basic mechanisms responsible for the elevation in blood pressure, would prevent counter-regulatory responses and would have minimal side-effects in both the short-term and the long-term, the latter being of particular importance to younger patients. These aspects were considered at the symposium "Mild hypertension. Current con­ troversies and new approaches" held at Titisee in West Germany, October 13-15 in 1983. The foundation for discussion was set with an exposition of the neural and hormonal regulation of blood pressure in normal man followed by a consideration of the possible pathophysiological mechanisms involved in patients with hypertension. Particular at­ tention was focused on the central nervous system and on effects governed by activity of the peripheral nervous system as these may well provide further opportunities for logical therapeutic intervention in clinical hypertension. The current management of mild to moderate hypertension was then reviewed.

Editors and Affiliations

  • Hypertension Center, Veterans Administration Center, Long Beach, USA

    M. A. Weber

  • Medical Unit, St. Mary’s Hospital Medical School, London, Great Britain

    C. J. Mathias

Bibliographic Information

  • Book Title: Mild hypertension

  • Book Subtitle: Current controversies and new approaches

  • Editors: M. A. Weber, C. J. Mathias

  • DOI: https://doi.org/10.1007/978-3-642-87506-9

  • Publisher: Steinkopff Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Dr. Dietrich Steinkopff Verlag, GmbH & Co. KG, Darmstadt 1984

  • Softcover ISBN: 978-3-7985-0647-3Published: 01 January 1984

  • eBook ISBN: 978-3-642-87506-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: VIII, 172

  • Number of Illustrations: 6 b/w illustrations

  • Topics: Cardiology

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