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Hormones and Human Breast Cancer

An Account of 15 Years Study

  • John Hayward

Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 24)

Table of contents

  1. Front Matter
    Pages I-XV
  2. Historical Developments

    1. John Hayward
      Pages 1-9
  3. Hormones in Treatment and Prophylaxis

    1. John Hayward
      Pages 10-31
    2. John Hayward
      Pages 32-51
    3. John Hayward
      Pages 52-68
    4. John Hayward
      Pages 69-92
    5. John Hayward
      Pages 93-98
  4. The Hormonal Environment and Hormone Assays

    1. John Hayward
      Pages 99-112
    2. John Hayward
      Pages 113-120
    3. John Hayward
      Pages 121-135
    4. John Hayward
      Pages 136-146
    5. John Hayward
      Pages 147-149
  5. Back Matter
    Pages 150-151

About this book

Introduction

Seventeen years ago Mr. HAYWARD came to work in the Breast Clinic at Guy's Hospital. At that time the influence of hormones on the progress of breast cancer was appreciated; the prescription of androgens and oestrogens in the treatment of the advanced case was well established, and the operations of adrenalectomy and hypo­ physectomy had recently been introduced. Nevertheless, the prevailing view of the nature of breast cancer was that it was a local malignancy which had to be eradicated before it spread too widely and only if that had occurred would the aid of hormones be enlisted. How these hormones worked was unknown, indeed, today, as Mr. HAY­ WARD points out, their mode of action is still unknown. What has happened, however, within the last seventeen years has been a change of emphasis in our views regarding the essential nature of this disease. Instead of breast cancer being considered primarily as a local fault spreading centrifugally, it is realised with increasing con­ viction that it is a generalised disease with local manifestations and that one of the principal, if not the principal, aberration from normality lies in the endocrine environ­ ment. That this philosophy is demanding increasing acceptance is due in a significant measure to Mr. HAYWARD'S own investigations. In this work he has had the devoted assistance of BRIDGET WOLFF of the Breast Clinic at Guy's Hospital and the expert collaboration of Dr. R. D. BULBROOK of the Imperial Cancer Research Fund.

Keywords

breast cancer cancer cancer research clinic hormones hospital

Authors and affiliations

  • John Hayward
    • 1
  1. 1.Breast ClinicGuy’s HospitalLondon S.E. 1England

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-87015-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 1970
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-87017-0
  • Online ISBN 978-3-642-87015-6
  • Series Print ISSN 0080-0015
  • Buy this book on publisher's site