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Axoplasmic Transport in Physiology and Pathology

  • Dieter G. Weiss
  • Alfredo Gorio

Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Table of contents

  1. Front Matter
    Pages I-XI
  2. General Properties of Axoplasmic Transport

    1. Dieter G. Weiss
      Pages 1-14
  3. The Physiological Role of Axoplasmic Transport

    1. Front Matter
      Pages 15-15
    2. Annica Dahlström
      Pages 16-20
    3. Mats Sandberg, Anders Hamberger, Ingemar Jacobsson, Jan-Olof Karlsson
      Pages 27-31
    4. Harold Gainer, James T. Russell, Michael J. Brownstein
      Pages 44-50
  4. The Role of Axoplasmic Transport in Growth and Regeneration

  5. Experimental Neuropathies and Axoplasmic Transport

    1. Front Matter
      Pages 91-91
    2. Bernard Droz, Monique Chretien, Françoise Souyri, Gilles Patey
      Pages 104-108
    3. John W. Griffin, Paul N. Hoffman, Donald L. Price
      Pages 109-118
    4. Archinto P. Anzil, Gerhard Isenberg, Georg W. Kreutzberg
      Pages 119-122
  6. Neuronal Pathology and Axoplasmic Transport

    1. Front Matter
      Pages 123-123
    2. Stephen Brimijoin, Peter James Dyck, Johannes Jakobsen, Edward H. Lambert
      Pages 124-130
    3. Pierre Dustin, Jacqueline Flament-Durand
      Pages 131-136
    4. Maurizio Vitadello, Jean-Yves Couraud, Raymonde Hässig, Alfredo Gorio, Luigi Di Giamberardino
      Pages 137-139
    5. Johan Sjöstrand, W. Graham McLean, Björn Rydevik
      Pages 140-145
  7. Axoplasmic Transport as a Tool in Neurophysiology and Neuroanatomy

    1. Front Matter
      Pages 159-159
    2. M. Cuénod, P. Bagnoli, A. Beaudet, A. Rustioni, L. Wiklund, P. Streit
      Pages 160-166
    3. Andreas Aschoff, Norbert Fritz, Michael Illert
      Pages 177-187
  8. Back Matter
    Pages 189-198

About these proceedings

Introduction

Cajal and contemporary scientists have laid the basis of the modem concepts of the organization of the nervous system: the cir­ cuits of the brain are made up of individual neurons which transfer information via specialized structures called synapses. Soma and den­ drites usually receive the inputs, then the signal is carried all along the axon to the target areas. To fulfIll this task several types of neurons have developed their unique geometry characterized by a large recep­ tive area (soma and dendrites) and an often very extensive distal branching with the axon terminals. The volume of cytoplasm which constitutes the neuronal periphery is often far larger than the cell body, where the synthetic machinery is located. It is one of the roles ofaxoplasmic transport to supply the periphery with proper material and to sustain the specialized structures necessary for the physiological activity of the neuron. Furthermore, it has become more and more clear that target areas also exert effects on the innervating neurons, and these effects are not only mediated via recurrent fibers. Synapses have been shown to be able to pick up material from the synaptic left which is then intra­ axon ally transported back to the cell body. This retrograde axoplasmic transport has therefore been recognized as another basic mechanism to convey signals from the periphery to the centre.

Keywords

Axoplasmatischer Transport Nervensystem /Erkrankung Nervous System Transport neurons physiology

Editors and affiliations

  • Dieter G. Weiss
    • 1
  • Alfredo Gorio
    • 2
  1. 1.Zoologisches InstitutUniversität MünchenMünchen 2Germany
  2. 2.Department of CytopharmacologyFidia Research LaboratoriesAbano Terme, PadovaItaly

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-85714-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 1982
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-85716-4
  • Online ISBN 978-3-642-85714-0
  • Series Print ISSN 0172-6625
  • Buy this book on publisher's site