Treatment with Gallopamil

Results of recent research on calcium antagonism

  • F. Bender
  • W. Meesmann
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-VIII
  2. D. Scrutinio, S. Iliceto, R. Lagioia, D. Accettura, N. Preziusi, F. Mastropasqua et al.
    Pages 117-126
  3. H. Eichstädt, O. Danne, H. P. Koch, M. Langer, M. Cordes, C. Schubert et al.
    Pages 143-150
  4. M. Zehender, T. Meinertz, A. Geibel, S. Hohnloser, C. Weiss, H. Just
    Pages 151-160
  5. G. Rettig, S. Sen
    Pages 161-170
  6. Guiseppe Specchia, F. Cobelli, L. Tavazzi, S. De Servi, M. Ferrario, S. Ghio et al.
    Pages 179-186

About these proceedings

Introduction

Calcium antagonists are currently the most extensively investigated drugs for the treatment of heart disease. They are used worldwide with great success and a comparatively low incidence of adverse reactions. The most prevalent and threatening diseases in modem industrialized societies - the various forms and complications of coronary arteriosclerosis and arterial hypertension - are amenable to treatment with calcium antagonists. The pharmacological spectrum of calcium antagonists is highly specific and was supplemen­ ted a few years ago by gallopamil, a verapamil analogue. The experimental work reported at this symposium was concerned with effects of gallopamil on the electrophysiology of the heart, particularly in acute myocardial ischemia. New therapeutic features of myocardial hypertrophy and hypertrophic cardiomyopathy are discussed. In medical practice, gallopa­ mil has proved particularly useful for the treatment of angina pectoris. Studies comparing gallopamil with other calcium antagonists are described to profile the properties of the drugs in terms of their specific therapeutic value. There is still a need for more differential therapeutic trials. This first international symposium on gallopamil was attended by experts from institutions devoted to theoretical and clinical research and general practice.

Keywords

angina pectoris arterial hypertension drugs electrophysiology heart heart disease hypertension physiology

Editors and affiliations

  • F. Bender
    • 1
  • W. Meesmann
    • 2
  1. 1.Medizinische Universitätsklinik und PoliklinikMünsterGermany
  2. 2.Institut für PathophysiologieUniversitätsklinikum EssenEssenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-85376-0
  • Copyright Information Steinkopff-Verlag Darmstadt 1989
  • Publisher Name Steinkopff
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-85378-4
  • Online ISBN 978-3-642-85376-0
  • About this book