Infection Control in Intensive Care Units by Selective Decontamination

The Use of Oral Non-Absorbable and Parenteral Agents

  • Hendrik K. F. van Saene
  • C. P. Stoutenbeek
  • Peter Lawin
  • I. McA. Ledingham
Conference proceedings

Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 7)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Foreword

    1. I. McA. Ledingham
      Pages 1-1
  3. Introduction

    1. H. K. F. van Saene
      Pages 3-4
  4. Pathogenesis

    1. Front Matter
      Pages 5-5
    2. Host Microorganism Relationship in Healthy People

      1. Hendrik K. F. van Saene, C. P. Stoutenbeek, Peter Lawin, I. McA. Ledingham
        Pages 25-26
    3. Host Microorganism Relationship in the Critically Ill

  5. The Conventional Approach to Infection Control

About these proceedings


Selective decontamination is a technique which combines short-term and long-term antimicrobials to prevent or treat the acquisition and subsequent carriage of microorganisms causing late colonization and infections. The antimicrobials are selective in that they leave the indigenous, mostly anaerobic flora more or less intact, whilst the effective decontamination provides a genuine breakthrough in the endogenous route of pathogenesis. The improvements in decontamination techniques presented here offer significant reduction in infection related morbidity and mortality among trauma patients.


Sepsis Trauma care infection intensive care intensive care unit mortality multiple organ failure prevention

Editors and affiliations

  • Hendrik K. F. van Saene
    • 1
  • C. P. Stoutenbeek
    • 2
  • Peter Lawin
    • 3
  • I. McA. Ledingham
    • 4
  1. 1.Medical Microbiology, RoyalLiverpool HospitalLiverpoolUK
  2. 2.Intensieve ZorgenOnze Lieve Vrouw GasthuisAmsterdamThe Netherlands
  3. 3.Klinik für Anästhesiologie und operative IntensivmedizinWestfälischen Wilhelms-UniversitätMünsterGermany
  4. 4.The Faculty of MedicineHealth Sciences UniversityAl AinUnited Arab Emirates

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-51041-3
  • Online ISBN 978-3-642-83752-4
  • Series Print ISSN 0933-6788
  • About this book