Tactics and Strategy in Cancer Treatment

1. Front Matter

   Pages I-XV

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2. Tactics

   1. Front Matter

      Pages 1-1

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   2. Surgery

      1. Effects of the Removal of the Regional Lymph Nodes on the Survival of Mice Bearing B16 Melanoma or EAkR Lymphosarcoma

         • F. Economides, M. Bruley-Rosset

         Pages 2-7

      2. Regional Lymph Node Dissection in Melanoma of the Limbs Stage I — A Cooperative International Trial (WHO Collaborating Centers for diagnosis and treatment of melanoma)

         • U. Veronesi

         Pages 8-8

   3. Chemontherapy

      1. Effectiveness of Murine Leukemia Chemotherapy According to the Immune State: Reconsideration of Correlations Between Chemotherapy, Tumour Cell Killing, and Survival Time

         • G. Mathé, O. Halle-Pannenko, C. Bourut

         Pages 9-12

      2. Chemotherapy of Tumours in Immuno-deprived Mice

         • A. J. S. Davies

         Pages 13-16

      3. Treatment of Malignant Gliomas and Brain Metastases in Adults Using a Combination of Adriamycine, VM 26, and CCNU Results of a Type II Trial

         • P. Pouillart, G. Mathé, T. Palangie, J. Lheritier, M. Poisson, P. Huguenin et al.

         Pages 17-28

   4. Immunotherapy

      1. Immunologic and Cytokinetic Parameters of BCG-Induced Growth Control of a Murine Leukemia

         • L. Olsson

         Pages 29-35

   5. Monitoring

      1. Biochemical Aids to Cancer Management

         • E. H. Cooper

         Pages 36-38

      2. Laboratory Testing for Cancer

         • L. H. Rees

         Pages 39-50

3. General Strategy

   1. Front Matter

      Pages 51-54

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   2. Leukemias and Hematosarcomas

      1. Treatment of Murine EAkR Lymphosarcoma by Surgery Combined With Systemic or Local Active BCG Immunotherapy Applied Repeatedly

         • F. Economides, M. Bruley-Rosset, G. Mathé

         Pages 56-61

      2. Interspersion of Cyclophosphamide and BCG in the Treatment of L1210 Leukemia and Lewis Tumor

         • G. Mathé, O. Halle-Pannenko, C. Bourut

         Pages 62-66

      3. Results in Children of Acute Lymphoid Leukemia: Protocol ICIG-ALL 9 Consisting of Chemotherapy for Only 9 Months Followed by Active Immunotherapy

         • G. Mathe, F. De Vassal, L. Schwarzenberg, M. A. Gil, M. Delgado, R. Weiner et al.

         Pages 67-77

      4. Active Immunotherapy in Leukemia With Neuraminidase-Modified Leukemic Cells*

         • J. G. Bekesi, J. F. Holland

         Pages 78-89

      5. Chemotherapy and Immunotherapy Interspersion: Clinical Studies in Acute Myeloblastic Leukaemia

         • J. A. Whittaker

         Pages 90-94

      6. Androgens and Long-Term Complete Remission in Acute Granulopoietic Leukemias

         • D. Hollard, R. Berthier, J. J. Sotto

         Pages 95-103

      7. Treatment by Radiophosphorus Versus Busulfan in Polycythemia Vera: A Randomized Trial (E.O.R.T.C.’s) “Leukemias and Hematosarcomas” Group

         • H. O. Klein, G. Mathé, M. Hayat

         Pages 104-109

      8. The Strategy of Treatment of Hodgkin’s Disease

         • B. Hœrni, J. Chauvergne, C. Lagarde

         Pages 110-113

   3. Solid Tumors

      1. Limb Preservation in Osteogenic Sarcoma: A Preliminary Report

         • N. Jaffe, H. Watts, E. Frei, D. Traggis, G. Vawter, K. Fellows

         Pages 114-122

Tactics is the art of combining the action of troops or the proper means of different arms with the object of obtaining the maximum success at combat. Strategy is the art of combining the action of aB the military forces with a view to victory. This work, wh ich publishes the communications at the Annual General Meeting of the EORTC, wh ich was held in Paris in lune 1976, was devoted to tactics and to the therapeutic strategy with a view to the recovery of cancer patients. Table of Contents v Preface . I. Tactics G. MATHE: Tactics in Cancer Treatment: Introduction 1 1. Surgery F. ECONOMIDES and M. BRULEy-RosSET: Effects of the Removal of the Regional Lymph Nodes on the Survival of Mice Bearing B16 Melanoma or EAkR Lymphosarcoma . 2 U. VERONESI: Regional Lymph Node Dissection in Melanoma of the Limbs. Stage I-A Cooperative International Trial . 8 2. Chemotherapy G. MATHE, O. HALLE-PANNENKO, and C. BOURUT: Effectiveness of Murine Leukemia Chemotherapy According to the Immune State: Reconsideration of Correlations Between Chemotherapy, Tumour Cell Killing, and Survival Time 9 A. J. S. DAVIES: C!"temotherapy of Tumours in Immuno-deprived Mice 13 P. POUILLART, G. MATHE, T. PALANGJE, J. LHERITIER, M. PmSSON, P. HUGUENIN, H. GAUTIER, P. MORIN, and R. PARROT: Treatment of Malignant Gliomas and Brain Metastases in Adults Using a Combination of Adriamycin, VM 26 and CCNU- Results of Type 11 Trial . 17 3. lmmunotherapy L. OLSSON: Immunologie and Cytokinetic Parameters of BCG-induced Growth Control of a Murine Leukemia .

• Chemotherapy
• Immunotherapy
• Krebs
• Radiotherapy
• surgery

• Institut de Cancérologie et d’Immunogénétique (INSERM), Hôpital Paul-Brousse, Villejuif, France

  Georges Mathé

• Paul-Vaillant Couturier and Institut Gustave-Roussy, Villejuif, France

  Georges Mathé

Policies and ethics