Immunologic Aspects of Testicular Function

  • Roberto E. Mancini

Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 9)

Table of contents

  1. Front Matter
    Pages I-IX
  2. Introduction

    1. Roberto E. Mancini
      Pages 1-2
  3. Experimental Immunologic Orchitis

    1. Roberto E. Mancini
      Pages 3-12
    2. Roberto E. Mancini
      Pages 13-16
    3. Roberto E. Mancini
      Pages 17-18
    4. Roberto E. Mancini
      Pages 19-21
    5. Roberto E. Mancini
      Pages 22-30
    6. Roberto E. Mancini
      Pages 31-37
    7. Roberto E. Mancini
      Pages 38-54
    8. Roberto E. Mancini
      Pages 55-58
  4. Clinical Immunologic Orchitis

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      Pages 59-65
    2. Roberto E. Mancini
      Pages 66-77
    3. Roberto E. Mancini
      Pages 78-82
    4. Roberto E. Mancini
      Pages 83-84
  5. Antisperm Antibodies in Male Infertility

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      Pages 85-90
    2. Roberto E. Mancini
      Pages 91-95
  6. Conclusions

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      Pages 96-98
  7. Back Matter
    Pages 99-116

About this book


It has become increasingly evident within the last few decades that immunologic factors are involved in some aspects of the reproductive process and hence in the physiology and pathology of the genital tract. The concept that immune phenomena participate in human reproduction is not new. There are examples throughout the history of man that immune phenomena may have influenced the reproductive process. For example, the Bible states that Sarah was sterile for a long time but conceived in the later years of her marriage. This could be interpreted to mean that continued exposure to her husband's ejaculated antigens re­ sulted in antibody response, sufficient to induce sterility. However, after continence of long duration, the antibody level declined and conception became possible. Another of speculation is Darwin's Descent of Man, which contains a number of state­ source ments to the effect that profligacy of women may account for their "small fertility". The inference is that repeated exposure to antigenic material in the ejaculate causes antibody responses that lead to infertility (KATSH and KATSH, 1965). This is directly related to the modern postulate that prostitutes do not conceive because of antisperm antibodies acquired by frequent contact with semen.


infertility pathology physiology reproduction

Authors and affiliations

  • Roberto E. Mancini
    • 1
  1. 1.Centro de Investigationes en Reproduccion, Facultad de Medicina - 10°P.Universidad de Buenos AiresBuenos AiresArgentina

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1976
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-80987-3
  • Online ISBN 978-3-642-80985-9
  • Series Print ISSN 0077-1015
  • Buy this book on publisher's site