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  • © 1995

Mathematical Modeling and Scale-up of Liquid Chromatography

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  • ISBN: 978-3-642-79541-1
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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xiii
  2. Introduction

    • Tingyue Gu
    Pages 1-3
  3. Literature Review

    • Tingyue Gu
    Pages 4-8
  4. Mass Transfer Effects

    • Tingyue Gu
    Pages 32-38
  5. Modeling of Affinity Chromatography

    • Tingyue Gu
    Pages 81-94
  6. References

    • Tingyue Gu
    Pages 121-123
  7. Back Matter

    Pages 125-129

About this book

Liquid chromatography has proved to be one of the most important tools for separations. Rapid development in biotechnology has increased the demand for chromatography in analytical, preparative and large scale applications. The understanding of the dynamics of chromatography is imperative for the scale-up. This book is a systematic treatment of the general rate models for various forms of liquid chromatography including adsorption, size exclusion, affinity, reversed phase, hydrophobic interaction, and radial flow chromatography. Thermodynamic and mass transfer effects in liquid chromatography are discussed. Applications of computer programs for the rate models are described and the procedures for the scale-up of preparative- and large-scale liquid chromatography using the general rate models are given.

Keywords

  • Biochemie
  • Biotechnologie
  • Chromatographie
  • Expression
  • Mathematical Modeling
  • Mathematische Modellierung von Systemen
  • biochemistry
  • biotechnology
  • chemical engineering
  • chemistry
  • chromatography
  • reaction

Authors and Affiliations

  • Dept. of Chemical Engineering, Stocker Center, Ohio University, Athens, USA

    Tingyue Gu

Bibliographic Information

Buying options

eBook
USD 74.99
Price excludes VAT (USA)
  • ISBN: 978-3-642-79541-1
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout