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Cardiomyopathies

Realisations and Expectations

  • J. F. Goodwin
  • E. G. J. Olsen

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. E. G. J. Olsen, J. F. Goodwin
      Pages 3-5
  3. Dilated Cardiomyopathy

    1. Front Matter
      Pages 7-7
    2. J. F. Goodwin
      Pages 9-18
    3. E. G. J. Olsen, S. E. Trotter
      Pages 19-26
    4. P. J. Richardson, H. J. F. Why
      Pages 27-45
    5. E. M. Gilbert, A. Di Lenarda, J. B. O’Connell
      Pages 46-63
  4. Hypertrophic Cardiomyopathy

    1. Front Matter
      Pages 65-65
    2. J. F. Goodwin
      Pages 67-84
    3. E. G. J. Olsen, S. E. Trotter
      Pages 85-93
    4. P. J. Richardson, H. J. F. Why
      Pages 94-107
    5. J. T. Stewart, W. J. McKenna
      Pages 108-143
  5. Restrictive Cardiomyopathy

    1. Front Matter
      Pages 145-145
    2. J. F. Goodwin
      Pages 147-164
    3. E. G. J. Olsen, S. E. Trotter
      Pages 165-172
    4. H. Acquatella
      Pages 173-189
  6. Amyloid Heart Disease and Others

    1. Front Matter
      Pages 191-191
  7. Experimental, Clinical, Immunological and Molecular Biological Research

  8. Back Matter
    Pages 307-315

About this book

Introduction

This book reviews the basic knowledge about the cardiomyopathies and re-enforces the well-known definitions and classification of cardiomyopathies and specific heart muscle diseases, respectively. It emphasizes the importance of maintaining the classification into hypertrophic, dilated and restrictive cardiomyopathies, even though there are exceptions. The term "realisations" in the title is used in the sense of "achievements" and alludes to the progress in the understanding of heart muscle diseases over the last three decades and also to the areas of knowledge still not fully explored, for example, the as yet un­ classified putative cardiomyopathies such as arrhythmogenic right ventricular dysplasia, long QT syndrome and syndrome X. The accurate and sensitive identification of major risk factors for sudden death in hypertrophic cardiomyopathy needs further study, as do the implications of a familial basis in some patients with dilated cardio­ myopathy. The "expectations" mentioned in the title centre around the molecular biological aspects of viral myocarditis and dilated cardio­ myopathy and their relationship to each other; around the auto­ immune basis for dilated cardiomyopathy and its implications for drug therapy and cardiac transplantation; and around molecular genetic techniques for identifying the genes involved in hypertrophic cardiomyopathy that will be developed further. These will have implications for pre-natal recognition and for diagnosis in early life in apparently fit and active persons, and offer better prospects of prevention and cure.

Keywords

ADP-ATP-carrier autoantibodies cardiomyopathy clinical research diagnosis gene genetics heart heart disease heart muscle disease prenatal diagnosis research transplantation treatment viral heart disease

Editors and affiliations

  • J. F. Goodwin
    • 1
  • E. G. J. Olsen
    • 2
  1. 1.Department of CardiologyRoyal Postgraduate Medical SchoolLondonUK
  2. 2.Department of HistopathologyRoyal Brompton National Heart and Lung Hospital LondonLondonUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-77598-7
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-77600-7
  • Online ISBN 978-3-642-77598-7
  • Buy this book on publisher's site