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Soft Tissue Tumors

  • D. Harms
  • D. Schmidt

Part of the Current Topics in Pathology book series (CT PATHOLOGY, volume 89)

Table of contents

  1. Front Matter
    Pages I-XII
  2. J. Treuner, M. Morgan
    Pages 17-30
  3. W. Mellin, A. Niezabitowski, M. Brockmann, J. Ritter, P. Wuisman, V. Krieg
    Pages 95-121
  4. W. A. Newton Jr.
    Pages 241-259
  5. A. O. Cavazzana, V. Ninfo, R. Tirabosco, A. Montaldi, R. Frunzio
    Pages 313-332
  6. C. D. M. Fletcher
    Pages 333-354
  7. C. D. M. Fletcher
    Pages 355-380
  8. Back Matter
    Pages 381-388

About this book

Introduction

Soft tissue tumors are a very heterogeneous group of tumors in terms of histogenesis, morphology, cytogenetics, molecular biology, clinical manifestation, and prognosis. Their spectrum is fascinating for morphologists and basic scientists alike. Yet precisely this variability in the morphologic manifestation of soft tissue tumors, specifically their histologic and cytologic patterns, presents great difficulties to any effort to categorize them. Although many soft tissue tumors are today defined not only by histology but also by immunohistochemical, cytogenetic, and molecular biological findings, the histogenesis of many soft tissue tumors, in particular malignant ones, continues to be unknown. This is associated with the fact that the actual precursor cells that lead to these tumors have frequently not yet been identified. For this reason, the customary classification of malignant soft tissue tumors is primarily not histogenetic, but actually according to the dominant phenotype, however characteristic it is. Of course, an exact morphologic examination of soft tissue tumors con­ tinues to be an essential prerequisite for making a diagnosis and determining a therapy. The use of a wide range of additional modern examination techniques, however, can make a substantial contribution toward more precisely defining the biological behavior of a tumor, which without doubt can have therapeutic implications.

Keywords

Classification Diagnose Diagnosis Klassifikation Molecular Genetics Molekulargenetik Prognose Prognosis Soft Tissue Tumors Weichteiltumoren cell classification cytogenetics differential diagnosis DNA embryo genetics Grading histology molecular biology molecular genetics sarcoma tissue tumor

Editors and affiliations

  • D. Harms
    • 1
  • D. Schmidt
    • 2
  1. 1.Institut für PaidopathologieKlinikum der Christian-Albrechts-UniversitätKielGermany
  2. 2.Institut für PathologieMannheimGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-77289-4
  • Copyright Information Springer-Verlag Berlin Heidelberg 1995
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-77291-7
  • Online ISBN 978-3-642-77289-4
  • Series Print ISSN 0070-2188
  • Buy this book on publisher's site