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Theoretical and Experimental Insights into Immunology

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. Alan S. Perelson

    1. Theoretical Division, Los Alamos National Laboratory, Los Alamos, USA

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  2. Gérard Weisbuch

    1. Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris Cédex 5, France

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Nato ASI Subseries H: (ASIH, volume 66)

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Table of contents (30 papers)

  1. From Molecular to Cellular Immunology

    1. Implications of Cooperativity and Dimensional Complexity for Immunological Recognition

      • Neil S. Greenspan, Laurence J. N. Cooper
      Pages 263-278

    2. Shannon Information as a Measure of Amino Acid Diversity

      • Samuel Litwin, Rita Jores
      Pages 279-287

    3. Experimental Strategies, Antigenicity and Interpretation of Intermolecular Interactions

      • Frederique Lisacek
      Pages 289-296

    4. Receptor — Ligand Interactions and Diffusion Effects

      • Stig I. Andersson
      Pages 297-305

  2. Theories and Applications to Clinical Immunology

    1. Front Matter

      Pages 307-307
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    2. Mathematical Modeling of the Immune Response During Acute Viral Infections

      • G. Bocharov, A. Romanyukha
      Pages 309-321

    3. Mimicking the Strategy of the Immune System: Insight Gained from Mathematics

      • Z. Agur, G. Mazor, I. Meilijson
      Pages 323-332

    4. Rash Theory

      • Lee A. Segel, Alan S. Perelson, James M. Hyman, Sidney N. Klaus
      Pages 333-352

    5. On Second Symmetry and Aids

      • Geoffrey W. Hoffmann, Tracy A. Kion
      Pages 353-364

    6. Superantigens, Alloreactivity, Immunologic Tolerance, and AIDS: A Unified Hypothesis

      • Haynes W. Sheppard, Michael S. Ascher
      Pages 365-378

    7. Paradoxical Effects of Suppressor T Cells in Adjuvant Arthritis: Neural Network Analysis

      • Henri Atlan, Irun R. Cohen
      Pages 379-395

    8. Idiotypic Regulation in Experimental Autoimmune Thyroiditis (EAT)

      • H. Tang, C. Bédin, B. Texier, J. Charreire
      Pages 397-408

  3. Repertoire Selection

    1. Front Matter

      Pages 409-409
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    2. The Secrets of Crypticity and its Relationship to Medical Problems: Autoimmune Disease, Transplantation and Cancer

      • Gilles Benichou, Vatsala Bhardwaj, Stephen P. Schoenberger, Eli E. Sercarz
      Pages 411-424

    3. Role of Cryptic Self Germline Encoded Ig Epitopes in the Selection of the T cell Repertoire

      • Jian-Jun Chen, Srinivas-Venkatesh Kaveri, Heinz Kohler
      Pages 425-436

    4. T Cell Repertoire in Autoreactive Immunoglobulin-Transgenic Mice

      • M. Zöller
      Pages 437-457

    5. Experimental and Theoretical Investigations on Idiotypic Mimicry

      • Alf Grandien, Antonio Coutinho, John Stewart
      Pages 459-475

  4. Back Matter

    Pages 477-480
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Keywords

About this book

Immunology is largely a science of observation and experimentation, and these approaches have lead to great increases in our knowledge of the genes, molecules and cells of the immune system. This book is an up-to-date discussion of the current state of modelling and theoretical work in immunology, of the impact of theory on experiment, and of future directions for theoretical research. Among the topics discussed are the function and evolution of the immune system, computer modelling of the humoral immune response and of idiotypic networks and idiotypic mimicry, T-cell memory, cryptic peptides, new views and models of AIDS and autoimmunity, and the shaping of the immune repertoire by early presented antigens and self immunoglobulin.

Editors and Affiliations

  • Theoretical Division, Los Alamos National Laboratory, Los Alamos, USA

    Alan S. Perelson

  • Laboratoire de Physique Statistique, Ecole Normale Supérieure, Paris Cédex 5, France

    Gérard Weisbuch

Bibliographic Information

  • Book Title: Theoretical and Experimental Insights into Immunology

  • Editors: Alan S. Perelson, Gérard Weisbuch

  • Series Title: Nato ASI Subseries H:

  • DOI: https://doi.org/10.1007/978-3-642-76977-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1992

  • Softcover ISBN: 978-3-642-76979-5Published: 16 December 2011

  • eBook ISBN: 978-3-642-76977-1Published: 29 June 2013

  • Series ISSN: 1010-8793

  • Edition Number: 1

  • Number of Pages: XVIII, 480

  • Topics: Immunology, Cell Biology, Cancer Research, Biochemistry, general

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