Anticlastogens in Mammalian and Human Cells

  • Erich Gebhart
  • Ruben M. Arutyunyan

Table of contents

  1. Front Matter
    Pages I-X
  2. Erich Gebhart, Ruben M. Arutyunyan
    Pages 1-6
  3. Erich Gebhart, Ruben M. Arutyunyan
    Pages 7-30
  4. Erich Gebhart, Ruben M. Arutyunyan
    Pages 31-84
  5. Erich Gebhart, Ruben M. Arutyunyan
    Pages 85-97
  6. Erich Gebhart, Ruben M. Arutyunyan
    Pages 99-100
  7. Back Matter
    Pages 101-125

About this book


Anticlastogens in Mammalian and Human Cells covers research on the protection of chromosomes from the action of chemical mutagens by use of natural and synthetic antimutagens, which, because of their specific action on clastogenic damage are called anticlastogens. Based on an introductory chapter on nature and mode of formation of chromosome aberrations induced by chemical and also physical mutagens, the action of anticlastogens is discussed in detail. A definition and delineation of the term anticlastogenesis is followed by considerations on the various possibilities of classifying anticlastogens. Attention is paid to the action of anticlastogens in mammalian and human cell culture systems, in vivo data on anticlastogens are presented in great detail, as are the actions of anticlastogens on induced sister chromatid exchanges in various test systems. A mainly historical side-glance at the action of anticlastogens on chromosome damage induced by ionizing radiation is taken. The practical consequences of the findings on anticlastogenic action are extensively discussed as aspects of further research.


Antimutagene Chromosom Mammalia antimutagenes cell cell culture chromosome chromosomes mutagen mutation

Authors and affiliations

  • Erich Gebhart
    • 1
  • Ruben M. Arutyunyan
    • 2
  1. 1.Institut für HumangenetikUniversität Erlangen-NürnbergErlangenGermany
  2. 2.Department of BiologyState University of YerevanYerevanUSSR

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1991
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-76231-4
  • Online ISBN 978-3-642-76229-1
  • Buy this book on publisher's site