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Pharmacology of Asthma

  • Clive P. Page
  • Peter J. Barnes

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 98)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. L. A. Laitinen, A. Laitinen
    Pages 1-25
  3. A. G. Alexander, J. W. Wilson, S. T. Holgate, A. B. Kay
    Pages 27-51
  4. P. J. Barnes, K. F. Chung, C. P. Page
    Pages 53-106
  5. I. W. Rodger, R. C. Small
    Pages 107-141
  6. P. J. Barnes
    Pages 143-166
  7. R. G. Goldie, J. W. Paterson, K. M. Lulich
    Pages 167-205
  8. C. G. A. Persson, R. Pauwels
    Pages 207-225
  9. S. F. Smith, C. P. Page, P. J. Barnes, R. J. Flower
    Pages 227-260
  10. A. Szczeklik, C. Virchow, M. Schmitz-Schumann
    Pages 291-314
  11. Back Matter
    Pages 315-322

About this book

Introduction

This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter­ nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma­ cological intervention. It is hoped this book will be invaluable for research scientists and clinic­ ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu­ tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .

Keywords

Atemwegeerkrankung Atmen asthma pathophysiology physiology

Editors and affiliations

  • Clive P. Page
    • 1
  • Peter J. Barnes
    • 2
  1. 1.Department of PharmacologyKing’s College University of LondonLondonGreat Britain
  2. 2.Department of Thoracic MedicineNational Heart and Lung InstituteLondonGreat Britain

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-75855-3
  • Copyright Information Springer-Verlag Berlin Heidelberg 1991
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-75857-7
  • Online ISBN 978-3-642-75855-3
  • Series Print ISSN 0171-2004
  • Series Online ISSN 1865-0325
  • Buy this book on publisher's site