Table of contents

  1. Front Matter
    Pages i-xi
  2. Stavros Busenberg, Kenneth Cooke
    Pages 1-10
  3. Stavros Busenberg, Kenneth Cooke
    Pages 11-78
  4. Stavros Busenberg, Kenneth Cooke
    Pages 79-142
  5. Stavros Busenberg, Kenneth Cooke
    Pages 143-170
  6. Stavros Busenberg, Kenneth Cooke
    Pages 171-229
  7. Back Matter
    Pages 231-248

About this book


Infectious diseases are transmitted through various different mechanisms including person to person interactions, by insect vectors and via vertical transmission from a parent to an unborn offspring. The population dynamics of such disease transmission can be very complicated and the development of rational strategies for controlling and preventing the spread of these diseases requires careful modeling and analysis. The book describes current methods for formulating models and analyzing the dynamics of the propagation of diseases which include vertical transmission as one of the mechanisms for their spread. Generic models that describe broad classes of diseases as well as models that are tailored to the dynamics of a specific infection are formulated and analyzed. The effects of incubation periods, maturation delays, and age-structure, interactions between disease transmission and demographic changes, population crowding, spatial spread, chaotic dynamic behavior, seasonal periodicities and discrete time interval events are studied within the context of specific disease transmission models. No previous background in disease transmission modeling and analysis is assumedand the required biological concepts and mathematical methods are gradually introduced within the context of specific disease transmission models. Graphs are widely used to illustrate and explain the modeling assumptions and results. REMARKS: NOTE: the authors have supplied variants on the promotion text that are more suitable for promotionin different fields (by virtue of different emphasis in the content). They are not enclosed, but in the mathematics editorial.


Endemic Thresholds Epidemic Models Nonlinear Systems Vertical Transmission dynamics infection infectious diseases mathematics population dynamics vaccination

Authors and affiliations

  • Stavros Busenberg
    • 1
  • Kenneth Cooke
    • 2
  1. 1.Department of MathematicsHarvey Mudd CollegeClaremontUSA
  2. 2.Department of MathematicsPomona CollegeClaremontUSA

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1993
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-75303-9
  • Online ISBN 978-3-642-75301-5
  • Series Print ISSN 0067-8821
  • Buy this book on publisher's site