Human Retrovirology

Facts and Concepts

  • Jörg Schüpbach

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 142)

Table of contents

  1. Front Matter
    Pages I-VII
  2. Jörg Schüpbach
    Pages 1-5
  3. Jörg Schüpbach
    Pages 12-18
  4. Jörg Schüpbach
    Pages 18-19
  5. Jörg Schüpbach
    Pages 27-35
  6. Jörg Schüpbach
    Pages 52-59
  7. Jörg Schüpbach
    Pages 59-70
  8. Back Matter
    Pages 83-115

About these proceedings

Introduction

This book gives a concise review of the known human retroviruses; the onco-retroviruses HTLV-1 and -2 and the AIDS-associated lentiviruses HIV-1 and -2. History, classification, general and genomic structure, and basic biologic facts of retroviruses are described in introductory chapters. Subsequent chapters deal with the epidemiology, disease spectrum, structure and functions of the viral genes and proteins of the individual viruses. A separate chapter describes the various humoral and cellular immune mechanisms in response to HIV and their use with respect to diagnosis and treatment. Special attention is given to the complicated pathogenesis of AIDS and the consequences with regard to therapy and vaccination. The book ends with a critical review of recent work suggesting a possible role of still other retroviruses in human disorders including malignancies, autoimmune, or neurologic diseases. The book is designed to give the reader a broad, but detailed view of human retroviruses and the diseases associated with them. It tries to connect the viral, immunologic, and pathologic aspects of these infections to unifying concepts - no quick answers though, but profound critical information on a complicated topic.

Keywords

AIDS HIV Immunschwäche diseases immunodeficiency infection infections pathogenese pathogenesis protein proteins retroviruses vaccination virology virus

Authors and affiliations

  • Jörg Schüpbach
    • 1
  1. 1.Swiss National Center for Retroviruses, Institute of Immunology and VirologyUniversity of ZurichZurichSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-75195-0
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-51850-1
  • Online ISBN 978-3-642-75195-0
  • Series Print ISSN 0070-217X
  • About this book