Post-Transcriptional Control of Gene Expression

  • John E. G. McCarthy
  • Mick F. Tuite

Part of the NATO ASI Series book series (volume 49)

Table of contents

  1. Front Matter
    Pages I-XIX
  2. mRNA Stability

    1. Murray P. Deutscher, Jiren Zhang
      Pages 1-11
    2. C. Ehretsmann, A. J. Carpousis, H. M. Krisch
      Pages 21-30
    3. Allan Jacobson, Agneta H. Brown, Janet L. Donahue, David Herrick, Roy Parker, Stuart W. Peltz
      Pages 45-54
    4. L. Minvielle-Sebastia, A. Petitjean, B. Winsor, N. Bonneaud, F. Lacroute
      Pages 55-64
    5. Joel G. Belasco, Ann-Bin Shyu, Michael E. Greenberg
      Pages 65-71
    6. David B. Stern, Chen Hsu-Ching, Cynthia C. Adams, Karen L. Kindle
      Pages 73-82
    7. Robert B. Petersen, Susan Lindquist
      Pages 83-91
  3. Antisense Regulation

  4. Transcriptional (Anti-)Termination

    1. Luis Kameyama, Leonor Fernandez, Gabriel Guarneros, Donald L. Court
      Pages 125-133
    2. T. Platt, C. A. Brennan, J. S. Butler, D. A. Campbell, P. P. Sadhale, P. Spear et al.
      Pages 135-144
  5. Translational Control

    1. N. Jacques, M. Chevrier-Miller, J. Guillerez, M. Dreyfus
      Pages 145-155
    2. John E. G. McCarthy, Birgit Gerstel, Karsten Hellmuth, Volker Lang, Brian Surin, Peter Ziemke
      Pages 157-168
    3. Matthew A. Firpo, Albert E. Dahlberg
      Pages 185-195

About these proceedings


The last ten years have witnessed a remarkable increase in our awareness of the importance of events subsequent to transcriptional initiation in terms of the regulation and control of gene expression. In particular, the development of recombinant DNA techniques that began in the 1970s provided powerful new tools with which to study the molecular basis of control and regulation at all levels. The resulting investigations revealed a diversity of post-transcriptional mechanisms in both prokaryotes and eukaryotes. Scientists working on translation, mRNA stability, transcriptional (anti)termination or other aspects of gene expression will often have met at specialist meetings for their own research area. However, only rarely do workers in different areas of post-transcriptional control/ regulation have the opportunity to meet under one roof. We therefore thought it was time to bring together leading representatives of most of the relevant areas in a small workshop intended to encourage interaction across the usual borders of research, both in terms of the processes studied, and with respect to the evolutionary division prokaryotes/eukaryotes. Given the breadth of topics covered and the restrictions in size imposed by the NATO workshop format, it was an extraordinarily difficult task to choose the participants. However, we regarded this first attempt as an experiment on a small scale, intended to explore the possibilities of a meeting of this kind. Judging by the response of the participants during and after the workshop, the effort had been worthwhile.


DNA Genaktivität Gene activity Gene regulation Genexpression Genregulation RNA Termination gene gene expression genes regulation transcription translation

Editors and affiliations

  • John E. G. McCarthy
    • 1
  • Mick F. Tuite
    • 2
  1. 1.Gesellschaft für Biotechnologische Forschung mbHBraunschweigGermany
  2. 2.Biological LaboratoryUniversity of KentCanterbury, KentEngland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1990
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-75141-7
  • Online ISBN 978-3-642-75139-4
  • About this book