Advertisement

Assessment of Inhalation Hazards

Integration and Extrapolation Using Diverse Data

  • Ulrich Mohr
  • David V. Bates
  • Donald L. Dungworth
  • Peter N. Lee
  • Roger O. McClellan
  • Francis J. C. Roe
Conference proceedings

Part of the ILSI Monographs book series (ILSI MONOGRAPHS)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Integrative Approach to Assessing Human Health Risk: Two Contemporary Problems

    1. Front Matter
      Pages 1-1
    2. R. O. McClellan, R. G. Cuddihy, W. C. Griffith, J. L. Mauderly
      Pages 3-22
  3. Types of Evidence: General Strengths and Weaknesses

    1. Front Matter
      Pages 37-37
    2. Epidemiological

    3. Animal

      1. G. A. Boorman, S. L. Eustis, M. R. Elwell, R. A. Griesemer
        Pages 61-68
    4. Dosimetric

    5. Mechanistic

  4. Case Studies

    1. Front Matter
      Pages 129-129
    2. Formaldehyde

    3. Arsenic

    4. Butadiene

      1. R. L. Melnick, J. E. Huff, R. A. Miller
        Pages 177-188
      2. R. J. Laib, S. Deutschmann, B. Jelitto, R. R. Vangala, R. Kreiling
        Pages 189-199
      3. G. M. Matanoski, C. Santos-Burgoa, S. L. Zeger, L. Schwartz
        Pages 201-214
    5. Benzene

      1. M. A. Medinsky
        Pages 215-224
      2. A. Jacobs
        Pages 225-231
    6. Mineral Fibers

    7. Environmental Tobacco Smoke

    8. Automotive Exhaust Emissions and Polycyclic Aromatic Hydrocarbons

  5. Interfaces Between Scientific Judgement and Prudent Environmental Health Policy

    1. Front Matter
      Pages 325-325
    2. P. W. Preuss, V. J. Cogliano, P. D. White
      Pages 337-347
    3. G. Rose
      Pages 349-356
  6. Some Reflections on the Symposium

    1. D. V. Bates, R. O. McClellan
      Pages 365-371
  7. Back Matter
    Pages 373-382

About these proceedings

Introduction

The International Life Sciences Institute (ILSI), a nonprofit, public foundation, was established in 1978 to advance the sciences of nutrition, toxicology, and food safety. ILSI promotes the resolution of health and safety issues in these areas by sponsoring research, conferences, publications, and educational programs. Through ILSI's programs, scientists from government, academia, and industry unite their efforts to resolve issues of critical importance to the public. As part of its commitment to understanding and resolving health and safety issues, ILSI is pleased to sponsor this series of monographs that consolidates new scientific knowledge, defines research needs, and provides a background for the effective application of scientific advances in toxicology and food safety. Alex Malaspina President International Life Sciences Institute Contents Series Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . xiii . . . . . . . . . . . . . Part I. Integrative Approach to Assessing Human Health Risk: Two Contemporary Problems Chapter 1. Integrating Diverse Data Sets to Assess the Risks of Airborne Pollutants . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 R.o. McClellan, R.G. Cuddihy, w.e. Griffith, and J. L. Mauderly Chapter 2. Risk Assessment for Radon Inhalation Based on Animal Exposure Data and Human Epidemiology . . . . . . . 23 . F. Steinhausler Part II. Types of Evidence: General Strengths and Weaknesses Section 1. Epidemiological Chapter 3. Inhalation Hazards: The Interpretation of Epidemiologic Evidence. . . . . . . . . . . . . . . . . . . . 39 . . . . . . . J.e. Bailar Chapter 4. Problems in Interpreting Epidemiological Data 49 P.N. Lee Section 2. Animal Chapter 5. Rodent Carcinogenicity Studies: Their Value and Limitations. . . . . . . . . . . . . . . . . . . . . . . . . . 61 . . . . . . . . . .

Keywords

Inhalation Toxicology Risk Assessment nutrition research toxicology

Editors and affiliations

  • Ulrich Mohr
    • 1
  • David V. Bates
    • 2
  • Donald L. Dungworth
    • 3
  • Peter N. Lee
    • 4
  • Roger O. McClellan
    • 5
  • Francis J. C. Roe
    • 6
  1. 1.Institut für Experimentelle PathologieMedizinische Hochschule HannoverHannover 61Germany
  2. 2.University of British ColumbiaVancouverCanada
  3. 3.Department of Veterinary PathologyUniversity of CaliforniaDavisUSA
  4. 4.P. N. Lee Statistics and Computing Ltd.Sutton, SurreyUK
  5. 5.Chemical Industry Institute of ToxicologyResearch Triangle ParkUSA
  6. 6.Wimbledon Common, LondonUK

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-74606-2
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74608-6
  • Online ISBN 978-3-642-74606-2
  • Buy this book on publisher's site