The Perception and Management of Drug Safety Risks

  • Bruno Horisberger
  • Rolf Dinkel

Part of the Health Systems Research book series (HEALTH)

Table of contents

  1. Front Matter
    Pages I-XXIII
  2. Opening Address

    1. J. Orsinger
      Pages 1-2
  3. Society and the Benefit/Risk Relationship

  4. Benefit/Risk Analysis and Appraisal

  5. Current Challenges

    1. Front Matter
      Pages 133-133

About this book

Introduction

In the past two decades public debate about the risks, benefits, and safety associated with drugs has intensified. Public disputes over risks are brought to court when individuals seek compensation for health problems attributed to a pharmaceutical product. The issue reaches legislatures and regulatory agencies when consumer advocates seek to influence the standards of drug usage. Front-page news tends to focus on accidents or other risk events with drugs. Drug risk and drug safety have become an important political issue. Drug regulat­ ory agencies have been instituted, and their responsibility has increased. The approval to market a drug is dependent on a set of sophisticated studies executed according to strict protocols and scientifically defined criteria. Drug surveillance activities have gained recognition, and reporting systems to identify drug safety problems have been strengthened. The understanding and management of drug safety is, nonetheless, beset by doubts, disagreements, and disputes. Conflict occurs over the significance of risk, the adequacy of evidence, the methodologies used to evaluate and measure risk, the standards that guide regulation, and the optimal means of communicating risk information to the public.

Keywords

assessment drug drug safety epidemiology health organizations pharmacology research

Editors and affiliations

  • Bruno Horisberger
    • 1
  • Rolf Dinkel
    • 2
  1. 1.Interdisciplinary Research Centre for Public HealthSt. GallenSwitzerland
  2. 2.HealthEcon Ltd.BaselSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-74272-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74274-3
  • Online ISBN 978-3-642-74272-9
  • Series Print ISSN 1431-4002
  • About this book