Protein Structure and Protein Engineering

  • Ernst-Ludwig Winnacker
  • Robert Huber
Conference proceedings

Table of contents

  1. Front Matter
    Pages I-XI
  2. W. P. Jencks
    Pages 1-5
  3. P. L. Privalov
    Pages 6-15
  4. R. Jaenicke
    Pages 16-36
  5. K. A. Dill, D. O. V. Alonso
    Pages 51-58
  6. T. A. Jones
    Pages 113-115
  7. A. Plückthun, A. Skerra, R. Glockshuber, J. Stadlmüller
    Pages 123-131

About these proceedings


Protein engineering has had considerable impact on basic and applied research in biochemistry and molecular biology. It is already in use as a tool in molecular biology, but it is beginning to strongly influence the planning of experiments in biology everywhere, and, with even fur­ ther-reaching consequences, the appointment politics in research in­ stitutions and industries. Protein engineering, perhaps more than any other methods of protein analysis and peptide synthesis, has shown that proteins are organic molecules governed by the universal laws of chemistry and physics. How­ ever, as was the case with other new powerful methods and techniques, protein engineering tempts to an exploration of its limitations and thus generates more questions than it answers. The 39th Mosbacher Colloquium on Protein Structure and Protein Engi­ neering is not the first conference on this topic and it will not be the last. The important issues are obviously techniques of protein en­ gineering, examples of application, and the basic framework of protein structure and stability within which reasonable experiments can be de­ signed; conversely also, what we can learn about protein structure, dynamics, and folding from such experiments. Experiments in this direc­ tion aim at elucidating the folding code in the long run, but help to exploit the role of individual amino acid residues in catalysis, pro­ tein stability, and binding specificity in selected proteins now.


ATP DNA DNA sequencing base enzymes mutagenesis protein reaction

Editors and affiliations

  • Ernst-Ludwig Winnacker
    • 1
  • Robert Huber
    • 2
  1. 1.Labor für Molekularbiologie, GenzentrumMartinsriedGermany
  2. 2.Max-Planck-Institut für BiochemieMartinsriedGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1988
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-74175-3
  • Online ISBN 978-3-642-74173-9
  • Series Print ISSN 0366-5887
  • Buy this book on publisher's site