Methods in Protein Sequence Analysis

Proceedings of the 7th International Conference, Berlin, July 3–8, 1988

  • Brigitte Wittmann-Liebold

Table of contents

  1. Front Matter
    Pages I-XXXV
  2. A Critical Evaluation of Sensitive Amino Acid Analysis

    1. Front Matter
      Pages 1-1
    2. H. E. Meyer, C. C. Kuhn, G. F. Meyer, K. Swiderek, C. Weber, E. Hoffmann-Posorske et al.
      Pages 19-22
  3. New Approaches for the Chemistry of the Edman Degradation

    1. Front Matter
      Pages 33-33
    2. Jin Shan-Wei, Xu Shan-Zhen, Zhang Xiu-Lan, Tang Tian-Bao
      Pages 34-41
    3. Hisashi Hirano, Brigitte Wittmann-Liebold
      Pages 42-51
    4. Wolf F. Brandt, Gerhard Frank
      Pages 52-59
  4. New Instrumentation in Sequence Analysis and Synthesis of Biopolymers

    1. Front Matter
      Pages 60-60
    2. Richard A. Laursen, James D. Dixon, Song-Ping Liang, Duc M. Nguyen, Terri Kelcourse, Lawrence Udell et al.
      Pages 61-68
    3. James M. Coull, James D. Dixon, Richard A. Laursen, Hubert Köster, Darryl Pappin
      Pages 69-78
    4. Ruedi H. Aebersold, Heinz Nika, Gary D. Pipes, Richard E. H. Wettenhall, Stephen M. Clark, Leroy E. Hood et al.
      Pages 79-97
    5. Stefan Fischer, Frank Reimann, Brigitte Wittmann-Liebold
      Pages 98-107
    6. R. J. Mattaliano, K. A. Yamada, J. K. Hughes, P.-M. Yuan
      Pages 112-115
  5. C-terminal Sequence Analysis: Alternative Techniques to the Stepwise Edman Degradation

  6. New Instrumentation and Approaches in Mass Spectrometry of Biopolymers

    1. Front Matter
      Pages 174-174
    2. Klaus Biemann, Richard S. Johnson, James A. Hill, Stephen A. Martin
      Pages 175-182
    3. Donald F. Hunt, Jeffrey Shabanowitz, John R. Yates III, Patrick R. Griffin, Nian Zhou Zhu
      Pages 183-190
    4. Peter Roepstorff, Klaus Klarskov, Peter Højrup
      Pages 191-198
    5. A. Benninghoven, B. Hagenhoff, R. Kock, G. Assman, M. Walter
      Pages 199-205
    6. Howard. R. Morris, Anne Dell, Maria Panico, Roy McDowell, Ashraf Chatterjee
      Pages 206-218
  7. HPLC Purification of Proteins and Peptides for Microsequences Analysis: Recovery of Proteins from Gels

    1. Front Matter
      Pages 219-219
    2. Guy Bauw, Marc Van den Bulcke, Jozef Van Damme, Magda Puype, Marc Van Montagu, Joël Vandekerckhove
      Pages 220-233
    3. Friedrich Lottspeich, Christoph Eckerskorn, Werner Mewes
      Pages 240-247
    4. Krishna Kalghatgi, Csaba Horváth
      Pages 248-255
    5. Richard J. Simpson, Geoffrey S. Begg, Gavin E. Reid, Michael R. Rubira, Larry D. Ward, Robert L. Moritz
      Pages 256-263
    6. Akira Tsugita, Masaharu Kamo, Carl S. Jone, Noriko Shikama
      Pages 280-283
    7. Annie Martin-Ponthieu, Danièle Wouters-Tyrou, Denise Bélaiche, Pierre Sautière
      Pages 289-292
  8. New Strategies of Protein and Peptide Characterization

About this book


"Methods in Protein Sequence Analysis - 1988" - contains selected contributions on modern protein- analytical techniques as presented by speakers at the Seventh International Conference on "Methods in Protein Sequence Analysis", held from July 3rd to July 8th, 1988 in Berlin. The book contains information on new methodologies for sensitive amino acid analysis, N- and C-terminal sequence analysis, and protein and peptide purification. In addition recent mass spectrometric approaches are described, as an alter­ native technique to the common stepwise degradative sequence analysis of polypeptides by the Edman method. The book presents new possibilities in the design of sequencers and sophisticated equipment for the structural analysis of peptides and proteins. It describes practical approaches for the investigation of protein domains and protein complexes, and contains review chapters on the crystallization of cell organelles as well as on recent theoretical aspects of protein folding mechanisms. The nature of protein folding is not yet understood, but further advances in this area would greatly enhance our present knowledge of protein structure and function. Further, the book gives examples of the application of gene technology to protein characterization and to the design of new proteins. This enables new studies on the structure and function of proteins to be made, and opens up efficient approaches to the design of drugs.


Amino acid Peptide primary structure proteins sequence analysis

Editors and affiliations

  • Brigitte Wittmann-Liebold
    • 1
  1. 1.Abteilung WittmannMax-Planck-Institut für Molekulare GenetikDahlemGermany

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1989
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-73836-4
  • Online ISBN 978-3-642-73834-0
  • Buy this book on publisher's site