Human Tumour Xenografts in Anticancer Drug Development

  • Benjamin Winograd
  • Michael Peckham
  • Herbert Michael Pinedo

Part of the ESO Monographs book series (ESO MONOGRAPHS)

Table of contents

  1. Front Matter
    Pages I-XV
  2. Biological Behaviour of Human Tumours Transplanted in Mice and the Evaluation of Therapeutic Response

  3. Prediction of Tumour Response for the Individual Patient by the Human Tumour Xenograft

    1. Front Matter
      Pages 23-23
  4. Prediction of Antitumour Activity per Tumour Type by the Human Tumour Xenograft

  5. Preclinical Evaluation of Analogs of Known Anticancer Agents

  6. New Drugs

    1. Front Matter
      Pages 79-79
    2. B. J. M. Braakhuis, A. Leyva, H. M. Pinedo, G. B. Snow
      Pages 81-83
  7. Human Tumour Xenografts in the Development of Biological Response Modifiers

    1. Front Matter
      Pages 89-89
    2. M. V. Pimm, J. A. Clegg, M. C. Garnett, R. W. Baldwin
      Pages 95-98
    3. H. E. Blythman, A. Bord, I. Buisson, O. Thurneyssen, G. Richer, F. K. Jansen
      Pages 103-107
  8. Human Tumour Xenografts in Drug Screening

    1. Front Matter
      Pages 109-109
    2. R. H. Shoemaker, T. L. McLemore, B. J. Abbott, D. L. Fine, E. Gorelik, J. G. Mayo et al.
      Pages 115-120
  9. Importance of Drug Resistance in Screening

    1. Front Matter
      Pages 121-121
    2. S. Merry, D. Cunningham, E. R. Courtney, T. Hamilton, S. B. Kaye, R. I. Freshney
      Pages 127-130
  10. Proferred Papers at the E.S.O. Seminar

    1. Front Matter
      Pages 131-131
    2. F. Darcel, M. Chatel, V. Quemener, J. Ph. Moulinoux
      Pages 134-134
    3. R. J. Fergusson, L. E. Anderson, J. F. Smyth
      Pages 135-135
    4. Ø. Fodstad, S. Aamdal, R. H. Shoemaker, A. Pihl
      Pages 136-136
    5. W. Hinkelbein, A. Wuerdinger, E. Wallbrecher, H. H. Fiebig
      Pages 137-137
    6. J. Hoogenhout, C. R. Jerusalem, J. J. M. Van Gasteren, H. B. Kal
      Pages 137-138
    7. L. Kopper, P. Nagy, J. Rajnay, K. Lapis
      Pages 138-138
    8. E. Tagliabue, S. Canevari, S. Menard, D. Mezzanzanica, R. Orlandi, M. Ripamonti et al.
      Pages 141-142

About these proceedings


Starting in 1986, the European School of Oncology has expanded its activities in post­ graduate teaching, which consisted mainly of traditional disease-orientated courses, by promoting new educational initiatives. One of these is the cloister seminars, short meet­ ings intended for highly qualified oncologists and dealing with specific, controversial aspects of clinical practice and research. Another is the institution of permanent study groups, also called task forces, where a limited number of leading experts are invited to meet once a year with the aim of defining the state of the art and possibly reaching a consensus on developments and treatment in specific fields of oncology. This series of ESO Monographs was designed with the specific purpose of disseminat­ ing the results of the most interesting of the seminars and study groups, and providing concise and updated reviews of the subjects discussed. It was decided to keep the layout very simple in order to keep costs to a minimum and make the monographs available in the shortest possible time, thus overcoming a com­ mon problem in medical literature: that of the material being outdated even before publication. Umberto Veronesi Chairman, Scientific Committee European School of Oncology Position Paper on the Application of Human Tumour Xenografts as a Model for Preclinical Phase" Studies in the Evaluation of New Anticancer Compounds Outcome of a seminar on Human Tumour Xenografts organised by the European School of Oncology, Milan, 26th-27th May, 1986.


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Editors and affiliations

  • Benjamin Winograd
    • 1
  • Michael Peckham
    • 2
  • Herbert Michael Pinedo
    • 3
  1. 1.EORTC New Drug Development OfficeFree University HospitalAmsterdamThe Netherlands
  2. 2.Central OfficeBritish Postgraduate Medical FederationLondonUK
  3. 3.Department of OncologyFree University HospitalAmsterdamThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1988
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-73254-6
  • Online ISBN 978-3-642-73252-2
  • Buy this book on publisher's site