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Molecular and Cellular Aspects of Erythropoietin and Erythropoiesis

  • Ivan N. Rich

Part of the NATO ASI Series book series (volume 8)

Table of contents

  1. Front Matter
    Pages I-VIII
  2. Preface

    1. Ivan N. Rich
      Pages 1-4
  3. Acknowledgements

    1. Ivan N. Rich
      Pages 5-5
  4. Abbreviations

    1. Ivan N. Rich
      Pages 6-8
  5. Molecular Biology of Erythropoiesis and Erythropoietin

    1. Front Matter
      Pages 9-9
    2. Eugene Goldwasser, Jeffrey McDonald, Nega Beru
      Pages 11-21
    3. Fu-Kuen Lin
      Pages 23-36
    4. P. R. Harrison, J. Frampton, I. Chambers, K. Kasturi, B. Thiele, D. Conkie et al.
      Pages 37-50
    5. C. Lacombe, N. Casadevall, J. Choppin, O. Muller, E. Goldwasser, B. Varet et al.
      Pages 61-72
    6. Sanford B. Krantz, Stephen T. Sawyer, Mark J. Kourny, Maurice C. Bondurant
      Pages 89-102
    7. Nicholas Hunt, Christine Laker, Carol Stocking, Norbert Hess, Peter Nobis, Jorn Sieb et al.
      Pages 103-121
    8. Back Matter
      Pages 122-125
  6. Cellular Interactions and Signals during Erythropoietic Ontogeny

  7. Cellular Interactions and Signals during Adult Erythropoiesis

  8. Assay of Erythropoietin

  9. Back Matter
    Pages 442-461

About these proceedings

Introduction

Molecular biology has provided a tool with which problems in cellular differentiation can be answered. Recombinant DNA technology has been used to obtain quantities of the erythropoietic hormone, erythropoietin. The availability of the hormone has provided a much-needed impetus in learning how erythropoiesis is controlled. Knowledge of the genetic components, transcription and translation of the erythropoietin gene and finally the release of the mature hormone under various physiological conditions should be forthcoming in the near future. This volume will give the reader some indication as to the different aspects of erythropoiesis. They include the regulation of production of the hormone under normal and abnormal conditions, ontogeny and cellular interactions and the assay of the hormone itself.

Keywords

DNA EPO Macrophages biology development enzyme enzymes gene gene expression gene transfer molecular biology protein synthesis regulation transcription translation

Editors and affiliations

  • Ivan N. Rich
    • 1
  1. 1.Abteilung für TransfusionsmedizinUniversität Ulm DRK BlutspendezentraleUlmGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-72652-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1987
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-72654-5
  • Online ISBN 978-3-642-72652-1
  • Buy this book on publisher's site