© 1986


  • Ernest C. Foulkes

Part of the Handbook of Experimental Pharmacology book series (HEP, volume 80)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. K. Matsumoto, K. Fuwa
    Pages 1-31
  3. A. L. Page, M. M. El-Amamy, A. C. Chang
    Pages 33-74
  4. E. C. Foulkes
    Pages 75-100
  5. A. Bernard, R. Lauwerys
    Pages 135-177
  6. J. H. Exon, L. D. Koller
    Pages 339-350
  7. I. S. Jamall, J. C. Smith
    Pages 351-361
  8. M. D. Enger, C. E. Hildebrand, J. Seagrave, R. A. Tobey
    Pages 363-396
  9. Back Matter
    Pages 397-402

About this book


The toxic properties of cadmium compounds have been well recognized in many species. There is little evidence to suggest a physiologic role for the metal. Rather, because of its long biologic half-life, cadmium acts as a cumulative poison, and even at quite low ambient concentrations, it can accumulate in mammals to values not insignificant in terms of critical toxic levels. The problem of cadmium toxicity has become especially important, as cadmium concentrations in the environment have begun to rise owing to a variety of human activities such as mining, the metallurgical industry, coal combustion, and the use of cadmium-containing fertilizers. It seemed appropriate, therefore, to assemble in one volume an up-to-date analysis of the mechanism of action of cadmium on biologic systems. Aspects of this field have repeatedly been reviewed in the past, and particular reference must be made to the volumes prepared by FRIBERG and collaborators from Sweden. Much outstanding work on cadmium has also been reported from Japan, and I am happy that investigators from both countries were able to contribute to the present volume. Obviously, this volume does not report a consensus by its contributors. The purpose of the work was to permit leading investigators in the field to present a critical review with sufficient documentation to support their interpretations and conclusions. A certain amount of overlap and disagreement between chapters was therefore unavoidable. The result, I hope, will be a useful state-of-the-art discussion.


absorption antibody cardiovascular system chemistry combustion documentation kidney kinetics metabolism nutrition poison resistance toxicity toxicology

Editors and affiliations

  • Ernest C. Foulkes
    • 1
  1. 1.Department of Environment Health(56)University of Cincinnati, College of MedicineCincinnatiUSA

Bibliographic information

  • Book Title Cadmium
  • Editors Ernest C. Foulkes
  • Series Title Handbook of Experimental Pharmacology
  • DOI
  • Copyright Information Springer-Verlag Berlin Heidelberg 1986
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-3-540-16025-0
  • Softcover ISBN 978-3-642-70858-9
  • eBook ISBN 978-3-642-70856-5
  • Series ISSN 0171-2004
  • Series E-ISSN 1865-0325
  • Edition Number 1
  • Number of Pages XIV, 400
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Pharmacology/Toxicology
  • Buy this book on publisher's site