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Biological Dosimetry

Cytometric Approaches to Mammalian Systems

  • Conference proceedings
  • © 1984

Overview

Editors:
  1. Wolfgang G. Eisert

    1. Arbeitsgruppe Zytometrie, Gesellschaft für Strahlen- und Umweltforschung mbH, Hannover 21, Germany
      Biologische Forschung, Dr. K. Thomae GmbH, Biberach-Riss, Germany

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  2. Mortimer L. Mendelsohn

    1. Biomedical Sciences Division, Lawrence Livermore National Laboratory, Livermore, USA

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Table of contents (30 papers)

  1. Front Matter

    Pages I-XVII
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  2. Cytogenetic Effects

    1. Front Matter

      Pages 1-1
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    2. An Overview of Radiation Dosimetry by Conventional Cytogenetic Methods

      • David C. Lloyd
      Pages 3-14

    3. Cytogenetic Effects in Human Lymphocytes as a Dosimetry System

      • Manfred Bauchinger
      Pages 15-24

    4. Flow Cytometric Detection of Aberrant Chromosomes

      • J. W. Gray, J. Lucas, L. C. Yu, R. Langlois
      Pages 25-35

    5. Flow Cytometric Measurement of Cellular DNA Content Dispersion Induced by Mutagenic Treatment

      • F. J. Otto, H. Oldiges, V. K. Jain
      Pages 37-49

    6. Flow Cytometric Analysis of Chromosome Damage After Irradiation: Relation to Chromosome Aberrations and Cell Survival

      • J. A. Aten, M. W. Kooi, J. Th. Bijman, J. B. A. Kipp, G. W. Barendsen
      Pages 51-59

    7. Chromosome Analysis of Leukemia and Preleukemia: Preliminary Data on the Possible Role of Environmental Agents

      • Herman van den Berghe
      Pages 61-65

    8. Radiation Dosimetry Using the Methods of Flow Cytogenetics

      • Daryll K. Green, Judith A. Fantes, George Spowart
      Pages 67-76

    9. Preliminary Reanalysis of Radiation-Induced Chromosome Aberrations in Relation to Past and Newly Revised Dose Estimates for Hiroshima and Nagasaki A-Bomb Survivors

      • Akio A. Awa, Toshio Sofuni, Takeo Honda, Howard B. Hamilton, Shoichiro Fujita
      Pages 77-82

  4. Mutagenic Effects

    1. Front Matter

      Pages 139-139
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    2. Biological Dosimetry of Mutagenesis: Principles, Methods, and Cytometric Prospects

      • Mortimer L. Mendelsohn
      Pages 141-148

    3. Detection of HGPRT-Variant Lymphocytes Using the FIP High-Speed Image Processor

      • P. E. Perry, E. J. Thomson, M. H. Stark, J. H. Tucker
      Pages 149-159

    4. Somatic Mutations Detected by Immunofluorescence and Flow Cytometry

      • R. H. Jensen, W. Bigbee, E. W. Branscomb
      Pages 161-170

    5. Computer Scoring of Micronuclei in Human Lymphocytes

      • H. Callisen, A. Norman, M. Pincu
      Pages 171-179
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Keywords

About this book

In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar­ row stem cells or spermatogonia.

Editors and Affiliations

  • Arbeitsgruppe Zytometrie, Gesellschaft für Strahlen- und Umweltforschung mbH, Hannover 21, Germany

    Wolfgang G. Eisert

  • Biologische Forschung, Dr. K. Thomae GmbH, Biberach-Riss, Germany

    Wolfgang G. Eisert

  • Biomedical Sciences Division, Lawrence Livermore National Laboratory, Livermore, USA

    Mortimer L. Mendelsohn

Bibliographic Information

  • Book Title: Biological Dosimetry

  • Book Subtitle: Cytometric Approaches to Mammalian Systems

  • Editors: Wolfgang G. Eisert, Mortimer L. Mendelsohn

  • DOI: https://doi.org/10.1007/978-3-642-69334-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1984

  • Softcover ISBN: 978-3-540-12790-1Published: 01 June 1984

  • eBook ISBN: 978-3-642-69334-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVII, 346

  • Number of Illustrations: 30 b/w illustrations

  • Topics: Pharmacology/Toxicology, Biological and Medical Physics, Biophysics, Pharmacy

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