Diagnosis and Therapy of Porphyrias and Lead Intoxication

1. Pathogenesis, Clinical Biochemistry, and Treatment of Chronic Hepatic Porphyrias

   1. Clinical Observation, Diagnostics, and Therapy for Symptomatic and Hereditary Porphyria Cutanea Tarda

      • G. C. Topi, L. D’Alessandro Gandolfo

      Pages 107-110

   2. Uroporphyrinogen Decarboxylase (Uro-D) Defect in Erythrocytes in Chronic Hepatic Porphyrias

      • R. v. Tiepermann, M. Doss

      Pages 111-116

   3. The Problem of Possible Etiological Factors in the Origin and Development of PCT

      • L. Malina, J. Chlumsky

      Pages 117-120

   4. Incidence of Porphyria in Slovenia

      • A. Kansky, M. Berčič

      Pages 121-124

   5. Chronic Hepatic Porphyrias and the Role of Iron in These Disorders

      • P. A. Lehr, R. M. Saenz

      Pages 125-126

   6. Chloroquine in the Treatment of Porphyria Cutanea Tarda

      • V. Kordač, M. Jirsa, M. Kaláb

      Pages 127-132

   7. Chloroquine Treatment of Porphyria Cutanea Tarda

      • M. Gebel, M. Doss, F. W. Schmidt

      Pages 133-135

   8. Clinical Importance of Suburoporphyrins

      • M. Jirsa, M. Kaláb, V. Kordač, H. Soldátová

      Pages 136-138

   9. Current Diagnostic Problems in the Cutaneous Porphyrias in Infancy. Presentation of Unusual Cases

      • L. D’Alessandro Gandolfo, G. C. Topi

      Pages 139-142

2. Porphyria and Environment

   1. Front Matter

      Pages 143-143

      PDF

   2. Influence of Environmental Factors on Porphyrin Metabolism

      • N. Simon, Cs. Siklósi, F. Kószó

      Pages 145-150

   3. Porphyrinogenic Action of Polyhalogenated Aromatic Compounds, With Special Reference to Porphyria and Environmental Impact

      • J. J. T. W. A. Strik

      Pages 151-164

   4. Lead Poisoning Attributable to Automobile Traffic

      • W. Blumer

      Pages 165-167

   5. Neoplasms and Metabolic Disturbances of Porphyrins in Rats With Chronic Experimental Lead Poisoning

      • B. Zawirska

      Pages 168-171

3. Diagnosis of Lead Intoxication

   1. Front Matter

      Pages 173-173

      PDF

   2. Time Course and Compartment Relations of Heme-Synthesis Disturbances Induced by Inorganic Lead Compounds in Humans

      • H. Schlegel, G. Kufner

      Pages 175-177

   3. Urinary Porphyrin Profiles in Acute Lead Poisoning: Relation to Differentiation From Acute Intermittent Porphyria

      • M. Doss, R. v. Tiepermann

      Pages 178-184

   4. Determination of Lead and Cadmium in Whole Blood by Electrothermal Atomic Absorption Spectroscopy

      • M. Stoeppler, K. Brandt

      Pages 185-187

   5. Biochemical Behavior of Delta-Aminolevulinic Acid Dehydratase During Chronic Oral Lead Poisoning in Sheep

      • C. P. Fassbender

      Pages 188-190

   6. Diagnostic Criteria of Increased Lead Absorption in Occupational Medicine

      • R. Schiele, K. H. Schaller

      Pages 191-197

On the occasion of the 450th anniversary of Philipp University, the porphyrin research group of. the Department of Clinical Biochemistry in the Faculty of Medicine organized an international symposium. This was held between June 28 and July 1, 1977, under the joint chairman­ ship of Professor Samuel Schwartz and the editor. The organizers and chairmen of the symposium wish to thank the Sozialminister of Hessen, Armin Clauss, the President of the German Society for Clinical Chemis­ try, Professor A. Delbrlick, and the Dean of the Faculty of Medicine of Philipp University, Professor F. Neurath, for their support and patronage. We are also grateful to Professor A. Treibs of the Institute of Organic Chemistry, Technical University of Munich. Professor Treibs, a former pupil, co-worker and now successor to the Nobel laureate Hans Fischer, kindly accepted the honorary presidency of this international symposium. The opening ceremony was inaugurated by the chairmen, with welcoming speeches by the President of Philipps University, Mr. Rudolf Zingel and patrons of the university. The editor outlined the 10 years of development of clinical biochemistry at Philipp University and traced in detail the continual development of its chief research effort in porphyria. It was pointed out that following the first international symposium on the regulation of porphyrin and heme biosynthesis in 1973 at Marburg (Doss, M. (ed. ): Regulation of Porphyrin and Heme Biosyn­ thesis.

• absorption
• anemia
• biochemistry
• carcinoma
• chemistry
• diagnosis
• diagnostics
• differential diagnosis
• embryo
• metabolism
• pathogenesis
• research
• therapy

• Department of Clinical Biochemistry, Faculty of Medicine, Philipp University of Marburg, Marburg, Federal Republic of Germany

  Manfred Doss

Policies and ethics