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Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung

  • W. Arber
  • W. Henle
  • P. H. Hofschneider
  • J. H. Humphrey
  • N. K. Jerne
  • P. Koldovský
  • H. Koprowski
  • O. Maaløe
  • R. Rott
  • H. G. Schweiger
  • M. Sela
  • L. Syruček
  • P. K. Vogt

Table of contents

  1. Front Matter
    Pages i-iii
  2. S. C. Bansal, B. R. Bansal, J. P. Boland
    Pages 45-76
  3. Rudolf Hausmann
    Pages 77-110
  4. Peter Starlinger, Heinz Saedler
    Pages 111-152
  5. Lothar G. Schneider, H. Diringer
    Pages 153-180
  6. Back Matter
    Pages 181-202

About this book

Introduction

Expression of an immune response is the net result of complex synergis­ tic and antagonistic activities performed by a variety of cell types. It includes macrophages, T and B populations which may interact in performance of a response, and suppressor cells interfering with it. Accordingly, a lack of res­ ponse may not necessarily indicate absence of immunocompetent cells, but rather nonexpression of competence. Thus, one should consider two possible situations, which are by no means mutually exclusive, to account for immuno­ logic unresponsiveness: (a) one or more of the cell populations composing the synergistic unit is absent or immature, and (b) an antagonistic unit which interferes with the response is dominating. In view of this, an approach to development of immune reactivity necessitates parallel surveys of development of cells with the potential to perform, as well as of cells which can suppress the response. Classification of the various cell types has been based so far on their phenotypic properties (e. g. , membrane antigen markers, cell receptors, pro­ duction and secretion of immunoglobulins, etc. ). Genotypically, T and B cells may represent either separate, independent cell lines, or different stages of development within the same cell lineage.

Keywords

Antigen Immunität biology cell immune response immunoglobulin immunology macrophages membrane microbiology population

Editors and affiliations

  • W. Arber
    • 1
  • W. Henle
    • 2
  • P. H. Hofschneider
    • 3
  • J. H. Humphrey
    • 4
  • N. K. Jerne
    • 1
  • P. Koldovský
    • 2
  • H. Koprowski
    • 2
  • O. Maaløe
    • 5
  • R. Rott
    • 6
  • H. G. Schweiger
    • 7
  • M. Sela
    • 8
  • L. Syruček
    • 9
  • P. K. Vogt
    • 10
  1. 1.BaselSwitzerland
  2. 2.PhiladelphiaUSA
  3. 3.MartinsriedGermany
  4. 4.LondonUK
  5. 5.CopenhagenDenmark
  6. 6.GießenGermany
  7. 7.WilbelmshavenGermany
  8. 8.RehovotIsrael
  9. 9.PragueCzech Republic
  10. 10.Los AngelesUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-66530-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1976
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-66532-5
  • Online ISBN 978-3-642-66530-1
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site