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Current Topics in Microbiology and Immunology / Ergebnisse der Microbiologie und Immunitätsforschung

  • W. Arber
  • R. Haas
  • W. Henle
  • P. H. Hofschneider
  • J. H. Humphrey
  • N. K. Jerne
  • P. Koldovský
  • H. Koprowski
  • O. Maaløe
  • R. Rott
  • H. G. Schweiger
  • M. Sela
  • L. Syruček
  • P. K. Vogt
  • E. Wecker

Table of contents

  1. Front Matter
    Pages i-iii
  2. H. Wigzell, P. Häyry
    Pages 1-42
  3. John E. Larsh Jr., Norman F. Weatherly
    Pages 113-137
  4. Back Matter
    Pages 139-164

About this book

Introduction

Prominent progress in molecular biology was only made when it became possible to separate functionally distinct molecules by taking advantage of their biophysical properties. Likewise, the analysis of the functions of hetero­ geneous populations of immunocompetent cells, as to the functional properties of their various subpopulations, can not be done until these can be isolated in reasonably pure form by selective fractionation. During the last few years significant advances have been made in this field, and cells have been separated according to size, density or charge (MILLER et aI. , 1969; SHORTMAN, 1968; ANDERSSON, 1973 c), or by taking advantage of more specific surface markers to allow selective depletion or enrichment of a given subpopulation of cells (WIGZELL and ANDERSSON, 1971). Although separation techniques have been used in a variety of cellular systems, they have been particularly useful in the study of reticuloendothelial cells and primarily in the study of cells partici­ pating in the immune responses. Quite extensive reviews have been written which well cover the methods used for separation of cells and the results obtained with the various approaches (WIGZELL and ANDERSSON, 1971; SHORTMAN, 1972). To review this work is becoming a more and more voluminous task. As data rapidly accumulate, we will not try to make such a complete review.

Keywords

Immunität biology immune response immunology microbiology molecular biology population

Editors and affiliations

  • W. Arber
    • 1
  • R. Haas
    • 2
  • W. Henle
    • 3
  • P. H. Hofschneider
    • 4
  • J. H. Humphrey
    • 5
  • N. K. Jerne
    • 1
  • P. Koldovský
    • 3
  • H. Koprowski
    • 3
  • O. Maaløe
    • 6
  • R. Rott
    • 7
  • H. G. Schweiger
    • 8
  • M. Sela
    • 9
  • L. Syruček
    • 10
  • P. K. Vogt
    • 11
  • E. Wecker
    • 12
  1. 1.BasleSwitzerland
  2. 2.FreiburgGermany
  3. 3.PhiladelphiaUSA
  4. 4.MartinsriedGermany
  5. 5.LondonUK
  6. 6.CopenhagenDenmark
  7. 7.GieβenGermany
  8. 8.WilhelmshavenGermany
  9. 9.RehovotIsrael
  10. 10.PragueCzech Republic
  11. 11.SeattleUSA
  12. 12.WürzburgGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-65912-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 1974
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-65914-0
  • Online ISBN 978-3-642-65912-6
  • Series Print ISSN 0070-217X
  • Buy this book on publisher's site