Metabolic Changes Induced by Alcohol

  • G. A. Martini
  • Ch. Bode

Table of contents

  1. Front Matter
    Pages I-X
  2. Metabolism of Alcohol and Alcohol Dehydrogenase

  3. Ethanol Induced Ultrastructural Alterations in the Liver

  4. Effect of Ethanol on Microsomal Functions

  5. Effect of Ethanol on Metabolites and Coenzymes of the Energy Producing Metabolism

  6. Effects of Ethanol on Carbohydrate Metabolism

    1. H. A. Krebs
      Pages 152-156

About this book

Introduction

In nearly all parts of the world, the consumption of alcohol is increasing, and the morbidity and mortality of diseases induced by alcohol are rising correspondingly. It has been stated that alcohol is consumed because it pro­ duces intoxication. This effect is due to its toxicological influence on the central nervous system with the resulting functional disturbances. For many years, the concept that alcoholic liver disease was of nutritional origin and only indirectly related to alcohol consumption and metabolism was accepted. Opinion has changed gradually in recent years and tends now to regard alcohol itself through its combustion, as responsible for many metabolic disorders. Interest in this problem has increased during the past decade, and numerous papers bearing on this subject have appeared. It seems that the oxidation of alcohol in the liver interferes in many ways with the intermediary metabolism of lipids, carbohydrates and proteins, including enzymes and hormones, and exerts damaging influence on the liver, the musculature, the heart, the brain and the kidneys. The "Workshop Symposium" brought together a limited number of the scientists involved in the new development, biochemists, physiologists, pharmacologists, pathologists and clinicians from eight European countries and from the United States and allowed a very lively and informal exchange. The symposium was honored by the presence of Sir Hans Krebs, whose vast experience stimulated the discussion. It is a great pleasure to dedicate this volume to Sir Hans on the occasion of his 70th birthday on August 25th.

Keywords

cancer central nervous system diseases heart mortality necrosis nervous system nutrition

Editors and affiliations

  • G. A. Martini
    • 1
  • Ch. Bode
    • 1
  1. 1.Medizinische Universitätsklinik Marburg355 Marburg/LahnGermany

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-65131-1
  • Copyright Information Springer-Verlag Berlin Heidelberg 1971
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-05296-8
  • Online ISBN 978-3-642-65131-1
  • About this book