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  • Conference proceedings
  • © 1997

Applied Toxicology: Approaches Through Basic Science

Proceedings of the 1996 EUROTOX Congress Meeting Held in Alicante, Spain, September 22–25, 1996

Part of the book series: Archives of Toxicology (TOXICOLOGY, volume 19)

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Table of contents (39 papers)

  1. Front Matter

    Pages I-IX
  2. The Gerhard Zbinden Memorial Lecture

    1. Front Matter

      Pages 1-1
  3. Detection of Chemically-Induced Changes in P53 Expression

    1. Front Matter

      Pages 15-15
    2. Looking at p53: Theoretical Implications and Methodological Aspects

      • Bertram Opalka, Sabine Kasimir-Bauer
      Pages 17-28
  4. Norman Aldridge Memorial Symposium

    1. Front Matter

      Pages 29-29
    2. Toxicologists versus Toxicological Disasters: Toxic Oil Syndrome, Clinical Aspects

      • A. Gómez de la Cámara, I. Abaitua Borda, M. Posada de la Paz
      Pages 31-40
    3. Epidemiology of the Toxic Oil Syndrome

      • Rossanne M. Philen, Manuel Posada de la Paz, Robert H. Hill, Helen H. Schurz, Ignacio Abaitua Borda, Agustín Gómez de la Cámara et al.
      Pages 41-52
    4. Analytical Measurements of Products of Aniline and Triglycerides in Oil Samples Associated with the Toxic Oil Syndrome

      • Helen H. Schurz, Robert H. Hill, Rossanne M. Philen, Manuel Posada de la Paz, Ignacio Abaitua Borda, Edwin M. Kilbourne et al.
      Pages 53-64
    5. Immunological Aspects of the Toxic Oil Syndrome

      • Carlos Lahoz, Victoria del Pozo, Soledad Gallardo, Blanca Cárdaba, Aurora Jurado, Isabel Cortegano et al.
      Pages 65-73
  5. Altered Gene Expression and Immunotoxicity

    1. Front Matter

      Pages 75-75
    2. Regulation and Mechanisms of Apoptosis in T Lymphocytes

      • Diels J. van den Dobbelsteen, C. Stefan I. Nobel, Andrew F. G. Slater, Sten Orrenius
      Pages 77-85
    3. Immunoregulatory Genes and Immunosuppression by Glucocorticoids

      • Nathalie Auphan, Joseph A. Didonato, Arno Helmberg, Caridad Rosette, Michael Karin
      Pages 87-95
    4. Molecular Aspects of UVB-lnduced Immunosuppression

      • Johan Garssen, Rob J. Vandebriel, Henk van Loveren
      Pages 97-109
  6. The Use of Ecotoxicology and Human Toxicology in the Regulation of Chemical Safety in the European Union

    1. Front Matter

      Pages 111-111
    2. The Identification of Thresholds of Acceptability and Danger: The Chemical Presence Route

      • Michael Matthies, Frank Koormann, Geert Boeije, Tom CJ Feijtel
      Pages 123-135
    3. The Environmental Experience: Ecosystem Protection

      • Finn Bro-Rasmussen
      Pages 155-166

About this book

This volume contains the main papers presented at the 1996 EUROTOX congress, Alicante, Spain, September 22-25,1996.
The understanding of toxicological events, such as the Spanish Toxic Oil Syndrome, or of intoxications by algal toxins draws heavily on the knowledge obtained from basic science. This is clearly reflected in the topics of Symposia and Workshops that deal with alterations in gene expression and immunotoxicity, prediction of individual susceptibility to toxicants, mechanisms of phototoxicity, protein targets of neurotoxicity, as well as mechanisms of carcinogenesis in transgenic mice. The application of basic science then allows better evaluation of the role of air pollution in allergy or a better assessment of progress in antidotic therapy. A pivotal role is fulfilled here by methodological aspects of the detection of changes in gene expression, challenges in analytical toxicology, or the development of in vitro models for the study of molecular mechanisms of toxicity.

Keywords

  • Immuntoxikologie
  • Mechanismen der Toxizität
  • Toxisches Öl-Syndrom
  • apoptosis
  • ecotoxicology
  • enzymes
  • gene expression
  • immunotoxicology
  • mechanisms of toxicity
  • neurotoxicity
  • toxic oil syndrome
  • transgene Tiere
  • transgenic animals
  • Ökotoxikologie

Editors and Affiliations

  • Interkantonale Kontrollstelle für Heilmittel, Switzerland

    Jürg P. Seiler

  • Dept. of Neurochemistry Campus San Juan, University of Alicante, Alicante, Spain

    Eugenio Vilanova

Bibliographic Information

  • Book Title: Applied Toxicology: Approaches Through Basic Science

  • Book Subtitle: Proceedings of the 1996 EUROTOX Congress Meeting Held in Alicante, Spain, September 22–25, 1996

  • Editors: Jürg P. Seiler, Eugenio Vilanova

  • Series Title: Archives of Toxicology

  • DOI: https://doi.org/10.1007/978-3-642-60682-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Softcover ISBN: 978-3-642-64505-1

  • eBook ISBN: 978-3-642-60682-3

  • Series ISSN: 0171-9750

  • Edition Number: 1

  • Number of Pages: XII, 417

  • Number of Illustrations: 2 illustrations in colour

  • Topics: Pharmacology, Immunology, Biochemistry, Cancer Biology

Buying options

eBook USD 119.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-60682-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 159.00
Price excludes VAT (USA)