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Molecular Signaling and Regulation in Glial Cells

A Key to Remyelination and Functional Repair

  • Conference proceedings
  • © 1997

Overview

Editors:
  1. Gunnar Jeserich

    1. FB Biologie/Chemie, Universität Osnabrück, Osnabrück, Germany

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  2. Hans H. Althaus

    1. Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany

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  3. Christiane Richter-Landsberg

    1. FB Biologie, Universität Oldenburg, Oldenburg, Germany

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  4. Rolf Heumann

    1. Molekulare Neurobiochemie, Universität Bochum, Bochum, Germany

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Table of contents (32 papers)

  1. Front Matter

    Pages I-XVI
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  2. Signaling for Glial Cells

    1. Front Matter

      Pages 1-1
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    2. Cytokines, Growth Factors and Their Intracellular Cascades

      1. Origins and early development of oligodendrocyte precursor cells
        • Nigel Pringle, Wei-Ping Yu, Ellen J. Collarini, Andy Calver, Anita Hall, Sarah Guthrie et al.
        Pages 3-10
      2. Cytokine and Growth Factor Synthesis in Human Astrocytes
        • Francesca Aloisi, Francesca Ceccherini Silberstein, Giulio Levi
        Pages 11-19
      3. Mature Pig Astrocytes Do Not Respond to NGF as Oligodendrocytes Do
        • Hans H. Althaus, Tyede Schmidt-Schultz, Sabine Klöppner
        Pages 20-27
      4. Endopeptidase-24.11/common acute lymphoblastic leukaemia antigen CD10 in Schwann cells: Evidence for a role in nerve development and regeneration
        • Rebecca Matsas, Stathis Meintanis
        Pages 28-43
      5. Regulation of Oligodendrocyte Development by the LIF Cytokine Subfamily: Studies of the Neonatal Lineage Cultured from Rat Cerebrum
        • Anthony Gard, Wesley Williams II, Martha Burrell
        Pages 44-56
      6. HIV-1 Env and Glutamate Induction of NO, IL1, and TNF
        • Jean E. Merrill, Bruce D. Howard, Nigel T. Maidment
        Pages 57-68
      7. Protein Kinase C Stimulation Induces Astrocyte and Oligodendrocyte Proliferation, Demyelination and Enhanced Remyelination in Aggregating Rat Brain Cell Cultures
        • Jean-Marie Matthieu, Sandrine Pouly, Paid Honegger
        Pages 69-75
      8. Monosialogangliosides and Nerve Growth Factor Stimulate Synthesis of Glycoproteins in Glioma Cells
        • Ephraim Yavin
        Pages 76-88

    3. Ion Channels and Neurotransmitter Receptors

      1. Responses of Oligodendrocytes to Classical Neurotransmitters: Signaling Pathways
        • Guillermina Almazan, Amani Khorchid, Hsueh-Ning Liu, Eduardo Molina-Holgado
        Pages 91-100
      2. Ion channel expression and function in astrocytic scars
        • Harald Sontheimer, Elizabeth Fernandez-Marques
        Pages 101-113
      3. Ion Channel Expression in Glial Cells from Trout Central Nervous System
        • H. Rabe, G. Glassmeier, T.-D. Nguyen, G. Jeserich
        Pages 114-126
      4. Ion Channel Reorganization During Remyelination
        • Peter Shrager, Sanja D. Novakovi
        Pages 127-138
      5. Gap Junction Expression in Myelinating Cells
        • Rolf Dermietzel
        Pages 139-148

  3. Genes and Proteins of Myelin

    1. Front Matter

      Pages 149-149
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    2. Structure, Regulations and Function

      1. CNS Myelination: What can we learn from phylogeny?
        • Robert M. Gould, Warren D. Spivack
        Pages 151-162
      2. The Proteolipid Protein Gene Family in the Central Nervous Systems of Fish
        • M. Yoshida, K. Kitagawa, D. R. Colman
        Pages 163-169
      3. Molecular Structure of Myelin Genes in the CNS of Trout
        • G. Jeserich, J. Strelau, A. Stratmann
        Pages 170-181
      4. Transcriptional Controls in the Oligodendrocyte Lineage
        • Lynn D. Hudson, Jin G. Kim, Claudia Wiese, Da-Lin Yao, Xia Liu, Henry F. de Webster et al.
        Pages 182-190
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Keywords

About this book

An excellent survey of the most recent advances in the area of cellular and molecular biology of glial cells and their involvement in remyelination and functional repair in the CNS. A major part of this book deals with signaling paths within and among neural cells. Glial cells (astrocytes, oligodentrocytes, microglial cells) themselves release substantial amounts of cytokines, growth factors and other signaling molecules, which play an important role during injury and regeneration. Another signaling route between neurons and glial cells follows ion channels and neurotransmitter receptors. In addition to animal models, human oligodentrocytes in cell culture and in the human MS brain are characterized with respect to their immunocytochemistry and function.

Editors and Affiliations

  • FB Biologie/Chemie, Universität Osnabrück, Osnabrück, Germany

    Gunnar Jeserich

  • Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany

    Hans H. Althaus

  • FB Biologie, Universität Oldenburg, Oldenburg, Germany

    Christiane Richter-Landsberg

  • Molekulare Neurobiochemie, Universität Bochum, Bochum, Germany

    Rolf Heumann

Bibliographic Information

  • Book Title: Molecular Signaling and Regulation in Glial Cells

  • Book Subtitle: A Key to Remyelination and Functional Repair

  • Editors: Gunnar Jeserich, Hans H. Althaus, Christiane Richter-Landsberg, Rolf Heumann

  • DOI: https://doi.org/10.1007/978-3-642-60669-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1997

  • Softcover ISBN: 978-3-642-64501-3Published: 19 September 2011

  • eBook ISBN: 978-3-642-60669-4Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XVI, 390

  • Topics: Neurosciences, Neurology, Cell Biology, Animal Physiology

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