Electric Field-Induced Effects on Neuronal Cell Biology Accompanying Dielectrophoretic Trapping

  • Tjitske Heida

Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 173)

Table of contents

  1. Front Matter
    Pages I-IX
  2. Tjitske Heida
    Pages 1-10
  3. Tjitske Heida
    Pages 31-46
  4. Tjitske Heida
    Pages 71-72
  5. Back Matter
    Pages 73-80

About this book

Introduction

 

The concept of the cultured neuron probe was induced by the possible selective stimulation of nerves for functional recovery after a neural lesion or disease. The probe consists of a micro-electrode array on top of which groups of neuronal cells are cultured. An efficient method to position groups of neuronal cells on top of the stimulation sites of the micro-electrode array is developed. With negative dielectrophoretic forces, produced by non-uniform electric fields on polarizable particles, neuronal cells are trapped. Experimental results and model simulations describe the trapping process and its effect on neuronal cell viability. 

Keywords

Cell Trapping Cultured Neuron Probe Dielectrophoresis Membrane Breakdown Nervous System cell biology

Authors and affiliations

  • Tjitske Heida
    • 1
  1. 1.Faculty of Electrical Engineering Mathematics and Computer Science, Laboratory of Measurement and Instrumentation, Laboratory of Biomedical EngineeringUniversity of TwenteEnschedeThe Netherlands

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-55469-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 2003
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-540-00637-4
  • Online ISBN 978-3-642-55469-8
  • Series Print ISSN 0301-5556
  • Series Online ISSN 2192-7065
  • About this book