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  • © 2015

Tactics in Contemporary Drug Design

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  • In each volume an overview chapter introduces the newcomer to the topic covered

  • Series covers hot topics of frontier research summarized by reputed scientists in the field

  • Review series is topic related Online version available on springerlink.com

Part of the book series: Topics in Medicinal Chemistry (TMC, volume 12)

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  • ISBN: 978-3-642-55041-6
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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. Physical Properties in Drug Design

    • Robert J. Young
    Pages 1-68
  3. Improving Solubility via Structural Modification

    • Michael A. Walker
    Pages 69-106
  4. Tactics to Avoid Inhibition of Cytochrome P450s

    • Andrew G. Leach
    Pages 107-158
  5. Drug Discovery vs hERG

    • Derek J Leishman, Zoran Rankovic
    Pages 225-259
  6. Drug-Induced Phospholipidosis: Prediction, Detection, and Mitigation Strategies

    • Umesh M Hanumegowda, Alicia Regueiro-Ren
    Pages 261-281
  7. Erratum to: Drug Discovery vs hERG

    • Derek J. Leishman, Zoran Rankovic
    Pages 385-385
  8. Back Matter

    Pages 391-394

About this book

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Keywords

  • application
  • drug design
  • inhibition

Editors and Affiliations

  • Bristol-Myers Squibb, Wallingford, USA

    Nicholas A. Meanwell

Bibliographic Information

Buying options

eBook
USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-55041-6
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book
USD 199.99
Price excludes VAT (USA)
Hardcover Book
USD 279.99
Price excludes VAT (USA)