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  • Book
  • © 2014

Mammalian Cell Cultures for Biologics Manufacturing

  • Covers trends in modern biotechnology

  • All aspects of this interdisciplinary technology, where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science, are treated

  • More information as well as the electronic version available at springer.com

  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Biochemical Engineering/Biotechnology (ABE, volume 139)

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eBook USD 349.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-54050-9
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book USD 449.99
Price excludes VAT (USA)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-viii
  2. Mammalian Cell Cultures for Biologics Manufacturing

    • Anne Kantardjieff, Weichang Zhou
    Pages 1-9
  3. Mammalian Cell Line Developments in Speed and Efficiency

    • Scott Estes, Mark Melville
    Pages 11-33
  4. Cell Culture Process Operations for Recombinant Protein Production

    • Susan Abu-Absi, Sen Xu, Hugh Graham, Nimish Dalal, Marcus Boyer, Kedar Dave
    Pages 35-68
  5. Equipment for Large-Scale Mammalian Cell Culture

    • Sadettin S. Ozturk
    Pages 69-92
  6. Development and Characterization of a Cell Culture Manufacturing Process Using Quality by Design (QbD) Principles

    • Daniel M. Marasco, Jinxin Gao, Kristi Griffiths, Christopher Froggatt, Tongtong Wang, Gan Wei
    Pages 93-121
  7. Mammalian Cell Culture Capacity for Biopharmaceutical Manufacturing

    • Dawn M. Ecker, Thomas C. Ransohoff
    Pages 185-225
  8. Back Matter

    Pages 257-259

About this book

Anne Kantardjieff and Weichang Zhou
Mammalian Cell Cultures for Biologics Manufacturing

Scott Estes and Mark Melville
Mammalian Cell Line Developments in Speed and Efficiency

Susan Abu-Absi, Sen Xu, Hugh Graham, Nimish Dalal, Marcus Boyer and Kedar Dave
Cell Culture Process Operations for Recombinant Protein Production

Sadettin S. Ozturk
Equipment for Large-Scale Mammalian Cell Culture

Daniel M. Marasco, Jinxin Gao, Kristi Griffiths, Christopher Froggatt, Tongtong Wang and Gan Wei
Development and Characterization of a Cell Culture Manufacturing Process Using Quality by Design (QbD) Principles

Michael J. Gramer
Product Quality Considerations for Mammalian Cell Culture Process Development and Manufacturing

Dayue Chen
Safety Assurance for Biologics Manufactured in Mammalian Cell Cultures: A Multitiered Strategy

Dawn M. Ecker and Thomas C. Ransohoff
Mammalian Cell Culture Capacity for Biopharmaceutical Manufacturing

Karthik P. Jayapal and Chetan T. Goudar
Transcriptomics as a Tool for Assessing the Scalability of Mammalian Cell Perfusion Systems

Enda Moran and Patrick Gammell
Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology

Keywords

  • Biologics
  • Biopharmaceutical Manufacturing
  • Cell Culture
  • Cell Culture Manufacturing
  • Cell Line Developments
  • Mammalian Cell
  • Mammalian Cell Perfusion Systems
  • Recombinant Protein Production
  • Review
  • Transcriptomics

Editors and Affiliations

  • WuXi AppTec Co., Ltd, Shanghai, People's Republic of China

    Weichang Zhou

  • Alexion Pharmaceuticals, Cheshire, USA

    Anne Kantardjieff

Bibliographic Information

Buying options

eBook USD 349.00
Price excludes VAT (USA)
  • ISBN: 978-3-642-54050-9
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Hardcover Book USD 449.99
Price excludes VAT (USA)