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Mammalian Cell Cultures for Biologics Manufacturing

  • Weichang Zhou
  • Anne Kantardjieff

Part of the Advances in Biochemical Engineering/Biotechnology book series (ABE, volume 139)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Anne Kantardjieff, Weichang Zhou
    Pages 1-9
  3. Scott Estes, Mark Melville
    Pages 11-33
  4. Susan Abu-Absi, Sen Xu, Hugh Graham, Nimish Dalal, Marcus Boyer, Kedar Dave
    Pages 35-68
  5. Sadettin S. Ozturk
    Pages 69-92
  6. Daniel M. Marasco, Jinxin Gao, Kristi Griffiths, Christopher Froggatt, Tongtong Wang, Gan Wei
    Pages 93-121
  7. Dawn M. Ecker, Thomas C. Ransohoff
    Pages 185-225
  8. Back Matter
    Pages 257-259

About this book

Introduction

Anne Kantardjieff and Weichang Zhou
Mammalian Cell Cultures for Biologics Manufacturing

Scott Estes and Mark Melville
Mammalian Cell Line Developments in Speed and Efficiency

Susan Abu-Absi, Sen Xu, Hugh Graham, Nimish Dalal, Marcus Boyer and Kedar Dave
Cell Culture Process Operations for Recombinant Protein Production

Sadettin S. Ozturk
Equipment for Large-Scale Mammalian Cell Culture

Daniel M. Marasco, Jinxin Gao, Kristi Griffiths, Christopher Froggatt, Tongtong Wang and Gan Wei
Development and Characterization of a Cell Culture Manufacturing Process Using Quality by Design (QbD) Principles

Michael J. Gramer
Product Quality Considerations for Mammalian Cell Culture Process Development and Manufacturing

Dayue Chen
Safety Assurance for Biologics Manufactured in Mammalian Cell Cultures: A Multitiered Strategy

Dawn M. Ecker and Thomas C. Ransohoff
Mammalian Cell Culture Capacity for Biopharmaceutical Manufacturing

Karthik P. Jayapal and Chetan T. Goudar
Transcriptomics as a Tool for Assessing the Scalability of Mammalian Cell Perfusion Systems

Enda Moran and Patrick Gammell
Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology

Keywords

Biologics Biopharmaceutical Manufacturing Cell Culture Cell Culture Manufacturing Cell Line Developments Mammalian Cell Mammalian Cell Perfusion Systems Recombinant Protein Production Review Transcriptomics

Editors and affiliations

  • Weichang Zhou
    • 1
  • Anne Kantardjieff
    • 2
  1. 1.WuXi AppTec Co., LtdShanghaiPeople's Republic of China
  2. 2.Alexion PharmaceuticalsCheshireUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-54050-9
  • Copyright Information Springer-Verlag Berlin Heidelberg 2014
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-642-54049-3
  • Online ISBN 978-3-642-54050-9
  • Series Print ISSN 0724-6145
  • Series Online ISSN 1616-8542
  • Buy this book on publisher's site