PET and SPECT in Psychiatry

1. Front Matter

   Pages i-xxi

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2. Basics

   1. Front Matter

      Pages 1-1

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   2. Neuroimaging in Psychiatric Drug Development and Radioligand Development for New Targets

      • Akihiro Takano, Christer Halldin, Lars Farde

      Pages 3-14

   3. PET Quantification in Neuropsychiatry

      • Michel Koole, Cindy Casteels, Koen Van Laere

      Pages 15-44

   4. Pharmacological Interventions That Have the Potential to Alter Neurotransmitter Levels in the Human Brain

      • Fokko J. Bosker, Janine Doorduin, Minke E. Jongsma, Anniek K. D. Visser, Joanna Udo de Haes, Thomas I. F. H. Cremers et al.

      Pages 45-63

   5. The Role of P-Glycoprotein in Psychiatric Disorders and in Psychiatric Treatment

      • Onno L. de Klerk

      Pages 65-90

3. Depression and Related Disorders

   1. Front Matter

      Pages 91-91

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   2. Molecular Imaging of Depressive Disorders

      • Henricus G. Ruhé, Anniek K. D. Visser, Vibe G. Frokjaer, Bartholomeus (Benno) C. M. Haarman, Hans C. Klein, Jan Booij

      Pages 93-172

   3. Functional Brain Imaging of Suicidal Behavior

      • Stefanie Desmyter, Stijn Bijttebier, Cornelis van Heeringen

      Pages 173-183

   4. SPECT and PET in Late-Life Depression

      • Tiago S. Vieira, Richard Oude Voshaar, Peter Paul De Deyn, Rudi A. J. O. Dierckx, Aren van Waarde

      Pages 185-208

   5. Neuroimaging in Seasons and Winter Depression

      • Christoph Spindelegger, Matthäus Willeit, Nicole Praschak-Rieder, Rupert Lanzenberger, Siegfried Kasper

      Pages 209-222

   6. Bipolar Disorders

      • Bartholomeus (Benno) C. M. Haarman, Rixt F. Riemersma Van der Lek, Henricus G. Ruhé, Jan Cees de Groot, Willem A. Nolen, Janine Doorduin

      Pages 223-251

   7. PET and SPECT in Psychiatric Complications of Parkinson’s Disease

      • Valtteri Kaasinen

      Pages 253-269

   8. Psychiatric Disorders in Dementia

      • Yannick Vermeiren, Debby Van Dam, Peter Paul De Deyn

      Pages 271-324

   9. Imaging of the Antidepressant Drug Response Using SPECT and PET

      • Ralf P. Clauss, Max Zöttl, Mike Sathekge

      Pages 325-345

4. Anxiety Disorders

   1. Front Matter

      Pages 347-347

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   2. Neurotransmission: A Review of PET and SPECT Studies in Anxiety Disorders

      • Mats Fredrikson, Vanda Faria, Tomas Furmark

      Pages 349-370

   3. Neurobiology of Posttraumatic Stress Disorder: The Role of Nuclear Neuroimaging

      • Alex G. G. Doruyter, Dan J. Stein, James M. Warwick

      Pages 371-395

   4. Neuroimaging in PTSD-Related Psychotherapies

      • Marco Pagani, Marco Cavallo

      Pages 397-410

   5. Dissociative Identity Disorder and Fantasy Proneness: A Positron Emission Tomography Study of Authentic and Enacted Dissociative Identity States

      • A. A. T. Simone Reinders, Antoon T. M. Willemsen

      Pages 411-431

PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects – such as suicide, sleep, eating disorders, and autism – are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.

• Functional Neuroimaging
• Nuclear Medicine Technology
• Psychiatric Disorders

“This book is part of a trilogy that deals with the applications of PET and SPECT in neurosciences … . We strongly recommend this book to … those working in neuroscience, such as psychiatrists, neurologists, geriatricians, nuclear physicians, neuroradiologists and psychologists. The book may also appeal and be useful to general practitioners, basic researchers and others. … should be available in all university libraries to act as bait to attract brilliant young minds to the field of neuroimaging.” (Gianluca De Matteis and Luigi Mansi, European Journal of Nuclear Medicine and Molecular Imaging, Vol. 42, 2015)

• Nuclear Medicine and Molecular Imaging, University Medical Center Groningen, Groningen, The Netherlands

  Rudi A.J.O. Dierckx, Erik F. J. de Vries, Aren Waarde

• Faculty of Electrical Engineering and Information Technology, University of Applied Sciences Offenburg, Offenburg, Germany

  Andreas Otte

• Department of Nuclear Medicine and Molecular Imaging, University Medical Center Groningen (UMCG), Groningen, The Netherlands

  Johan A. den Boer