Overview
- Provides a comprehensive review of the multitude of nucleic acid polymerases
- Catalogs all nucleic acid polymerases
- Written by polymerase fans for polymerase fans?
- Includes supplementary material: sn.pub/extras
Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 30)
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About this book
This book provides a review of the multitude of nucleic acid polymerases, including DNA and RNA polymerases from Archea, Bacteria and Eukaryota, mitochondrial and viral polymerases, and other specialized polymerases such as telomerase, template-independent terminal nucleotidyl transferase and RNA self-replication ribozyme. Although many books cover several different types of polymerases, no book so far has attempted to catalog all nucleic acid polymerases. The goal of this book is to be the top reference work for postgraduate students, postdocs, and principle investigators who study polymerases of all varieties. In other words, this book is for polymerase fans by polymerase fans.
Nucleic acid polymerases play a fundamental role in genome replication, maintenance, gene expression and regulation. Throughout evolution these enzymes have been pivotal in transforming life towards RNA self-replicating systems as well as into more stable DNA genomes. These enzymes are generally extremely efficient and accurate in RNA transcription and DNA replication and share common kinetic and structural features. How catalysis can be so amazingly fast without loss of specificity is a question that has intrigued researchers for over 60 years. Certain specialized polymerases that play a critical role in cellular metabolism are used for diverse biotechnological applications and are therefore an essential tool for research.
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Table of contents (14 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
Bibliographic Information
Book Title: Nucleic Acid Polymerases
Editors: Katsuhiko S. Murakami, Michael A. Trakselis
Series Title: Nucleic Acids and Molecular Biology
DOI: https://doi.org/10.1007/978-3-642-39796-7
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2014
Hardcover ISBN: 978-3-642-39795-0Published: 31 October 2013
Softcover ISBN: 978-3-662-50998-2Published: 23 August 2016
eBook ISBN: 978-3-642-39796-7Published: 22 October 2013
Series ISSN: 0933-1891
Series E-ISSN: 1869-2486
Edition Number: 1
Number of Pages: VIII, 342
Number of Illustrations: 23 b/w illustrations, 53 illustrations in colour
Topics: Enzymology, Nucleic Acid Chemistry, Gene Expression, Cell Biology