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Neurogenesis and Neural Plasticity

  • Catherine Belzung
  • Peter Wigmore

Part of the Current Topics in Behavioral Neurosciences book series (CTBN, volume 15)

Table of contents

  1. Front Matter
    Pages i-x
  2. Yan Gu, Stephen Janoschka, Shaoyu Ge
    Pages 31-48
  3. Gilles Gheusi, Gabriel Lepousez, Pierre-Marie Lledo
    Pages 49-72
  4. Mariana Carasatorre, Víctor Ramírez-Amaya
    Pages 73-115
  5. Andrea Gómez-Palacio-Schjetnan, Martha L. Escobar
    Pages 117-136
  6. Timothy J. Schoenfeld, Elizabeth Gould
    Pages 139-164
  7. Carmen Vivar, Michelle C. Potter, Henriette van Praag
    Pages 189-210
  8. Michael W. Marlatt, Michelle C. Potter, Thomas A. Bayer, Henriette van Praag, Paul J. Lucassen
    Pages 313-340
  9. Sébastien Couillard-Després
    Pages 343-355
  10. R. C. Trueman, A. Klein, H. S. Lindgren, M. J. Lelos, S. B. Dunnett
    Pages 357-398
  11. Back Matter
    Pages 399-401

About this book

Introduction

Neurogenesis and synaptogenesis, once thought to occur mainly during development, have now been established as key features of adult brain function.  Together they enable the brain to respond to both internal and external changes, giving the brain a previously unrecognised level of flexibility.  Alterations in these two features can produce improvements in cognition but are also critically involved in the pathological responses of the brain seen in many psychiatric and neurological conditions. 

This volume brings together authors working on a wide range of topics to provide an up to date account of the underlying mechanisms and functions of neurogenesis and synaptogenesis in the adult brain.  Ongoing neurogenesis and alterations in synapses are required for many functions of the brain including olfaction and hippocampal dependent memory.  Increased levels of synaptogenesis and neurogenesis are key aspects of the improved cognition seen after environmental enrichment and exercise.  However, changes in these features are also critical to the pathological response of the brain to stress, depression, neurodegeneration and cytotoxic drugs. 

With an increasing understanding of the role of neurogenesis and synaptogenesis it is possible to envisage improvements or novel treatments for a number of diseases and the possibility of harnessing these phenomena to reduce the impact of ageing and to provide mechanisms to repair the brain.  

Keywords

Hippocampus Neurogenesis Neurotrophin Synaptogenesis

Editors and affiliations

  • Catherine Belzung
    • 1
  • Peter Wigmore
    • 2
  1. 1., INSERM 930Faculté des SciencesToursFrance
  2. 2.Medical School, Queen's Medical CentreUniversity of NottinghamNottinghamUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-36232-3
  • Copyright Information Springer-Verlag Berlin Heidelberg 2013
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-642-36231-6
  • Online ISBN 978-3-642-36232-3
  • Series Print ISSN 1866-3370
  • Series Online ISSN 1866-3389
  • Buy this book on publisher's site