Overview
- Gives a comprehensive and up to date overview on the field
- Written by experts in the field
- First book to look in detail on the evolution of ECM
- Includes supplementary material: sn.pub/extras
Part of the book series: Biology of Extracellular Matrix (BEM)
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About this book
The evolution of single cells into multicellular organisms was mediated, in large part, by the extracellular matrix. The proteins and glycoconjugates that make up the extracellular matrix provide structural support to cellular complexes, facilitate cell adhesion and migration, and impart mechanical properties that are important for tissue function. Each class of ECM macromolecule has evolved to incorporate distinctive properties that are defined by conserved modules that are mixed together to achieve appropriate function. This volume provides a comprehensive analysis of how the major ECM components evolved over time in order to fill their specific roles found in modern organisms. The major focus is on the structural matrix proteins, matricellular proteins, and more complex ECM structures such as basement membranes. Adhesive proteins and their receptors are also discussed.
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
Bibliographic Information
Book Title: Evolution of Extracellular Matrix
Editors: Fred W. Keeley, Robert P. Mecham
Series Title: Biology of Extracellular Matrix
DOI: https://doi.org/10.1007/978-3-642-36002-2
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2013
Hardcover ISBN: 978-3-642-36001-5Published: 28 March 2013
Softcover ISBN: 978-3-642-43037-4Published: 04 April 2015
eBook ISBN: 978-3-642-36002-2Published: 15 March 2013
Series ISSN: 0887-3224
Series E-ISSN: 2191-1959
Edition Number: 1
Number of Pages: X, 290
Topics: Cell Biology, Evolutionary Biology, Cell Physiology