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Breast Cancer Biology for the Radiation Oncologist

  • Jonathan Strauss
  • William Small
  • Gayle E. Woloschak

Part of the Medical Radiology book series (MEDRAD)

Also part of the Radiation Oncology book sub series (Med Radiol Radiat Oncol)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Sara E. Barnato, William J. Gradishar
    Pages 1-6
  3. Kinnari Pandya, Clodia Osipo
    Pages 7-13
  4. Ruta Rao, Mashrafi Ahmed, William T. Leslie
    Pages 15-34
  5. Jian Jian Li
    Pages 49-57
  6. Camille Green, Atif J. Khan, Bruce G. Haffty
    Pages 71-80
  7. Bryan M. Rabatic
    Pages 81-90

About this book

Introduction

Breast Cancer Biology for the Radiation Oncologist is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist.

Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable.

All of these emerging issues of central importance to radiation oncologists are extensively discussed in this book, and practical treatment recommendations based on available clinical evidence are presented whenever possible.

Keywords

Biological subtypes of breast cancer Biology of DCIS Cancer Stem Cells and Radiotherapy Experimental therapies in breast cancer Herceptin Oncogene amplification

Editors and affiliations

  • Jonathan Strauss
    • 1
  • William Small
    • 2
  • Gayle E. Woloschak
    • 3
  1. 1.Department of Radiation OncologyNorthwestern UniversityChicagoUSA
  2. 2.Division of Radiation Oncology, Stritch School of MedicineCardinal Bernardin Cancer CenterChicagoUSA
  3. 3.Dept. RadiologyNorthwestern University Feinberg School of MedicineChicagoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-31220-5
  • Copyright Information Springer-Verlag Berlin Heidelberg 2015
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-642-31219-9
  • Online ISBN 978-3-642-31220-5
  • Series Print ISSN 0942-5373
  • Series Online ISSN 2197-4187
  • Buy this book on publisher's site