Ion Channels and Their Inhibitors

  • Satya Prakash Gupta

Table of contents

  1. Front Matter
    Pages i-xiii
  2. M. Michael Gromiha, Yu-Yen Ou, Shu-An Chen
    Pages 1-32
  3. Patrick Bois, Aurelien Chatelier, Jocelyn Bescond, Jean-François Faivre
    Pages 33-51
  4. Supa Hannongbua, Witcha Treesuwan, Warabhorn Boonyarat
    Pages 53-78
  5. Valentina Zuliani, Laura Amori, Mirko Rivara
    Pages 79-115
  6. Qidong You, Qian Yang, Xiaojian Wang
    Pages 117-147
  7. Jitendra N. Singh, Shyam S. Sharma
    Pages 149-190
  8. Andrea Schiesaro, Gerhard F. Ecker
    Pages 191-239
  9. Brij K. Sharma, Prithvi Singh, Yenamandra S. Prabhakar
    Pages 241-264
  10. Dimitra Hadjipavlou-Litina
    Pages 265-288
  11. C. Gopi Mohan, Ashish Pandey, Jignesh Mungalpara
    Pages 289-308
  12. Satya P. Gupta, Preet K. Kaur
    Pages 309-339
  13. Back Matter
    Pages 341-348

About this book

Introduction

Being the crucial components of living cells, ion channels are important targets of therapeutic agents. Historically, it has been challenging to develop drugs on this target class. A major issue with target based ion channel drug development is the identification of effective small chemical leads for medicinal chemistry optimization to the clinical candidate status. Thus enough attention has been paid to the study of structure and functions of ion channels and their potential inhibitors. The present book compiles important chapters authored by eminent workers in the field to cover important recent advances in the studies of the structure and functions of ion channels and their inhibitors, such as sodium ion, potassium ion, chloride ion, calcium ion channel inhibitors. The book may be of great use to the students and scientists working in the area of molecular biology, biochemistry, physiology, neurobiology, and medicinal chemistry.

Keywords

Calcium Ion Channels Chloride Ion Channel Inhibitors HCN Channels Ion Channel Blockers Ion Channels Membrane Proteins Potassium Ion Channel Inhibitors QSAR Sodium Ion Channel Inhibitors

Editors and affiliations

  • Satya Prakash Gupta
    • 1
  1. 1., Dept. of Pharmaceutical TechnologyMeerut Institute of Engineering and TechMeerutIndia

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-19922-6
  • Copyright Information Springer-Verlag Berlin Heidelberg 2011
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Chemistry and Materials Science
  • Print ISBN 978-3-642-19921-9
  • Online ISBN 978-3-642-19922-6
  • About this book