A Guide to Blood and Marrow Transplantation

  • H. Joachim Deeg
  • Hans-Georg Klingemann
  • Gordon L. Phillips
  • Gary Van Zant

Table of contents

  1. Front Matter
    Pages I-XII
  2. Introduction

    1. H. J. Deeg
      Pages 1-3
  3. Pretransplant Considerations

    1. Front Matter
      Pages 5-5
    2. H.-G. Klingemann
      Pages 15-25
    3. G. Van Zant
      Pages 27-34
    4. G. L. Phillips
      Pages 35-46
    5. H. J. Deeg, G. L. Phillips
      Pages 47-50
  4. Transplant Procedure

    1. Front Matter
      Pages 51-51
    2. G. L. Phillips
      Pages 53-67
    3. G. Van Zant
      Pages 69-79
    4. G. Van Zant
      Pages 81-85
    5. G. Van Zant, H. J. Deeg
      Pages 87-91
    6. H.-G. Klingemann
      Pages 93-99
  5. Transplant-Related Problems

    1. Front Matter
      Pages 101-101
    2. G. L. Phillips
      Pages 103-114
    3. H. J. Deeg
      Pages 115-125
    4. H. J. Deeg
      Pages 127-141
    5. G. L. Phillips
      Pages 143-158
    6. H.-G. Klingemann
      Pages 159-181

About this book

Introduction

This book provides an introduction to marrow and peripheral blood stem cell transplantation (including cord blood transplants), emphasizing the principles of this rapidly evolving area. A brief historical perspective is given and the latest developments are discussed. Particular attention is given to the rationale and indications for transplantation, the selection of donors and source of stem cells, and the separation, expansion and manipulation of stem cells. Essential aspects of histocompatibility, preparative regimens used in stem cell transplantation, the use of hematopoietic growth factors and cytokines, the pathophysiology of the graft-versus-host reaction, and the management of complications are dealt with. This book should provide the practicing internist, pediatrician, hematologist, and oncologist as well as other physicians in training or in practice, physicians' assistants, nurses, and students with the information necessary to understand the concepts of stem cell transplantation and to include transplantation in the treatment planning soon after a diagnosis has been established. The text should also be useful to the physician who resumes the patients' care when they return from the transplant center.

Keywords

blood bone marrow cancer therapy cell hematopoietic stem cell hematopoietic stem cell transplantation leukemia oncology organ prevention rehabilitation stem cell stem cell transplantation stem cells transplantation

Authors and affiliations

  • H. Joachim Deeg
    • 1
  • Hans-Georg Klingemann
    • 2
  • Gordon L. Phillips
    • 3
  • Gary Van Zant
    • 4
  1. 1.Fred Hutchinson Cancer Research CenterSeattleUSA
  2. 2.Section of Bone Marrow Transplantation Rush-Presbyterian-St. Luke’s Medical CenterChicagoUSA
  3. 3.BMT Program Markey Cancer CenterUniversity of KentuckyLexingtonUSA
  4. 4.Blood and Marrow Transplant Program University of Kentucky Medical CenterLexingtonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-18248-8
  • Copyright Information Springer-Verlag Berlin Heidelberg 1999
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Springer Book Archive
  • Print ISBN 978-3-642-62122-2
  • Online ISBN 978-3-642-18248-8
  • About this book