Prostate Cancer Imaging. Computer-Aided Diagnosis, Prognosis, and Intervention

International Workshop, Held in Conjunction with MICCAI 2010, Beijing,China, September 24, 2010. Proceedings

  • Anant Madabhushi
  • Jason Dowling
  • Pingkun Yan
  • Aaron Fenster
  • Purang Abolmaesumi
  • Nobuhiko Hata
Conference proceedings Prostate Cancer Imaging 2010

Part of the Lecture Notes in Computer Science book series (LNCS, volume 6367)

Table of contents

  1. Front Matter
  2. Jurgen J. Fütterer
    Pages 1-3
  3. Henkjan Huisman, Pieter Vos, Geert Litjens, Thomas Hambrock, Jelle Barentsz
    Pages 4-14
  4. Yusuf Artan, Masoom A. Haider, Imam Samil Yetik
    Pages 15-24
  5. Jason Dowling, Jonathan Lambert, Joel Parker, Peter B. Greer, Jurgen Fripp, James Denham et al.
    Pages 25-33
  6. Oscar Acosta, Jason Dowling, Guillaume Cazoulat, Antoine Simon, Olivier Salvado, Renaud de Crevoisier et al.
    Pages 42-51
  7. Samuel Kadoury, Pingkun Yan, Sheng Xu, Neil Glossop, Peter Choyke, Baris Turkbey et al.
    Pages 52-62
  8. A. D. Ward, C. Crukley, C. McKenzie, J. Montreuil, E. Gibson, J. A. Gomez et al.
    Pages 66-76
  9. Jun Xu, Rachel Sparks, Andrew Janowczyk, John E. Tomaszewski, Michael D. Feldman, Anant Madabhushi
    Pages 77-88
  10. Bikash Sabata, Boris Babenko, Robert Monroe, Chukka Srinivas
    Pages 89-100
  11. Daniel Cohen, Erik Mayer, Dongbin Chen, Ann Anstee, Justin Vale, Guang-Zhong Yang et al.
    Pages 101-110
  12. Soumya Ghose, Arnau Oliver, Robert Martí, Xavier Lladó, Jordi Freixenet, Joan C. Vilanova et al.
    Pages 111-120
  13. Ahmad Firjany, Ahmed Elnakib, Ayman El-Baz, Georgy Gimel’farb, Mohamed Abo El-Ghar, Adel Elmagharby
    Pages 121-130
  14. Yan Zhang, Bogdan J. Matuszewski, Aymeric Histace, Frédéric Precioso, Judith Kilgallon, Christopher Moore
    Pages 131-142
  15. Back Matter

About these proceedings

Introduction

Prostatic adenocarcinoma (CAP) is the second most common malignancy with an estimated 190,000 new cases in the USA in 2010 (Source: American Cancer Society), and is the most frequently diagnosed cancer among men. If CAP is caught early, men have a high, five-year survival rate. Unfortunately there is no standardized ima- based screening protocol for early detection of CAP (unlike for breast cancers). In the USA high levels of prostate-specific antigen (PSA) warrant a trans-rectal ultrasound (TRUS) biopsy to enable histologic confirmation of presence or absence of CAP. With recent rapid developments in multi-parametric radiological imaging te- niques (spectroscopy, dynamic contrast enhanced MR imaging, PET, RF ultrasound), some of these functional and metabolic imaging modalities are allowing for definition of high resolution, multi-modal signatures for prostate cancer in vivo. Distinct com- tational and technological challenges for multi-modal data registration and classifi- tion still remain in leveraging this multi-parametric data for directing therapy and optimizing biopsy. Additionally, with the recent advent of whole slide digital sc- ners, digitized histopathology has become amenable to computerized image analysis. While it is known that outcome of prostate cancer (prognosis) is highly correlated with Gleason grade, pathologists often have difficulty in distinguishing between interme- ate Gleason grades from histopathology. Development of computerized image analysis methods for automated Gleason grading and predicting outcome on histopathology have to confront the significant computational challenges associated with working these very large digitized images.

Keywords

Active Appearance Model Computer-Aided Design (CAD) HCI MRI augmented reality biopsy classification computer-aided diagnosis histoloy images image registration image retrieval image segmentation model morphology prostate imaging

Editors and affiliations

  • Anant Madabhushi
    • 1
  • Jason Dowling
    • 2
  • Pingkun Yan
    • 3
  • Aaron Fenster
    • 4
  • Purang Abolmaesumi
    • 5
  • Nobuhiko Hata
    • 6
  1. 1.Department of Biomedical EngineeringRutgers UniversityPiscatawayUSA
  2. 2.CSIRO Australian e-Health Research CentreRoyal Brisbane and Women’s HospitalHerstonAustralia
  3. 3.Philips Research North AmericaBriarcliff ManorUSA
  4. 4.Imaging Research LaboratoriesRobarts Research InstituteLondonCanada
  5. 5.Department of Electrical and Computer EngineeringUniversity of British ColumbiaVancouverCanada
  6. 6.Brigham and Women’s Hospital and Harvard Medical SchoolSt., BostonUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-3-642-15989-3
  • Copyright Information Springer-Verlag Berlin Heidelberg 2010
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Computer Science
  • Print ISBN 978-3-642-15988-6
  • Online ISBN 978-3-642-15989-3
  • Series Print ISSN 0302-9743
  • Series Online ISSN 1611-3349
  • About this book